tert-butyl (4R)-4-(bromomethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

Base Information

Chemical Name:tert-butyl (4R)-4-(bromomethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
CAS No.:1260610-79-4
Molecular Formula:C₁₁H₂₀BrNO₃
Molecular Weight:294.189
Hs Code.:

Synonyms:tert-butyl (4R)-4-(bromomethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate;(R)-tert-Butyl 4-(bromomethyl)-2,2-dimethyloxazolidine-3-carboxylate

Suppliers and Price of tert-butyl (4R)-4-(bromomethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 7 raw suppliers

Chemical Property of tert-butyl (4R)-4-(bromomethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

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Technology Process of tert-butyl (4R)-4-(bromomethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

There total 2 articles about tert-butyl (4R)-4-(bromomethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 108149-63-9
4-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester

: 857906-94-6,1260610-79-4
4-bromomethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

Guidance literature:: With carbon tetrabromide; In dichloromethane; at 0 - 20 ℃;
DOI:10.1081/SCC-200057988

Reference yield:

: 95715-86-9,108149-60-6
(S)-2,2-dimethyl-oxazolidine-3,4-dicarboxylic acid 3-tert-butyl ester 4-methyl ester

: 857906-94-6,1260610-79-4
4-bromomethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / NaBH₄ / methanol / 12 h / 20 °C

2: 63 percent / CBr₄ / CH₂Cl₂ / 0 - 20 °C

With sodium tetrahydroborate; carbon tetrabromide; In methanol; dichloromethane;
DOI:10.1081/SCC-200057988