4-Hydroxy-4-hydroxyMethylpiperidine hydrochloride

Base Information

• Chemical Name: 4-Hydroxy-4-hydroxyMethylpiperidine hydrochloride
• CAS No.: 240401-25-6
• Molecular Formula: C6H14ClNO2
• Molecular Weight: 167.636
• Mol file: 240401-25-6.mol

Synonyms:4-ethynylbenzyl alcohol;4-hydroxymethylphenylacetylene;Benzenemethanol,4-ethynyl;

Chemical Property of 4-Hydroxy-4-hydroxyMethylpiperidine hydrochloride

Chemical Property:

• PSA: 52.49000
• LogP: 0.22400
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

4-(Hydroxymethyl)piperidin-4-olhydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Hydroxy-4-hydroxyMethylpiperidine hydrochloride

There total 3 articles about 4-Hydroxy-4-hydroxyMethylpiperidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxy-4-(hydroxymethyl)-1-(phenylmethyl)piperidine (92197-36-9) → 4-hydroxy-4-hydroxymethylpiperidine hydrochloride (240401-25-6)

Guidance literature:

With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃;

Reference yield:

→ 4-hydroxy-4-hydroxymethylpiperidine hydrochloride (240401-25-6)

Guidance literature:

Reference yield:

→ 4-hydroxy-4-hydroxymethylpiperidine hydrochloride (240401-25-6) + 4-(3-Chloro-4-methoxybenzyl)amino-6-cyano-1-[4-hydroxy-4-(hydroxymethyl)piperidino]phthalazine Hydrochloride (240399-25-1)

Guidance literature:

upstream raw materials:

4-hydroxy-4-(hydroxymethyl)-1-(phenylmethyl)piperidine

Downstream raw materials:

(S)-1-{2-[1-(4-fluorophenyl)indolylethylamino]-6-(aminopyrazine-2-ylamino)pyrimidinecarboxylic-4-yl}-4-(hydroxymethyl)-4-ol

(S)-8-{2-[1-(4-fluorophenyl)ethyl]-6-(pyrazin-2-ylamino)pyrimidin-4-yl}-1,3-dioxo-8-azaspiro[4.5]decane-2-one

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