Benzyl methyl(piperidin-4-yl)carbamate

Base Information

Chemical Name:Benzyl methyl(piperidin-4-yl)carbamate
CAS No.:553672-39-2
Molecular Formula:C₁₄H₂₀N₂O₂
Molecular Weight:248.325
Hs Code.:2933399090
DSSTox Substance ID:DTXSID601246867
Mol file:553672-39-2.mol

Synonyms:benzyl methyl(piperidin-4-yl)carbamate;553672-39-2;Methyl-piperidin-4-yl-carbamic acid benzyl ester;benzyl N-methyl-N-piperidin-4-ylcarbamate;BENZYL METHYLPIPERIDIN-4-YLCARBAMATE;SCHEMBL785743;TQR0175;GEKZBJSBKRVWFF-UHFFFAOYSA-N;DTXSID601246867;benzylmethyl(piperidin-4-yl)carbamate;MFCD06656644;AKOS022178340;AM100943;BS-17582;DB-071986;benzyl N-methyl-N-(piperidin-4-yl)carbamate;CS-0151260;Phenylmethyl N-methyl-N-4-piperidinylcarbamate;A25826;D82766

Suppliers and Price of Benzyl methyl(piperidin-4-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
benzylmethyl(piperidin-4-yl)carbamate 95%
5g
$ 684.00

American Custom Chemicals Corporation
BENZYL-METHYL(PIPERIDIN-4-YL)CARBAMATE 95.00%
5MG
$ 498.30

Ambeed
Benzylmethyl(piperidin-4-yl)carbamate 95%
1g
$ 262.00

Ambeed
Benzylmethyl(piperidin-4-yl)carbamate 95%
250mg
$ 111.00

Ambeed
Benzylmethyl(piperidin-4-yl)carbamate 95%
5g
$ 810.00

Alichem
Benzylmethyl(piperidin-4-yl)carbamate
5g
$ 783.24

Total 7 raw suppliers

Chemical Property of Benzyl methyl(piperidin-4-yl)carbamate

Chemical Property:

PSA：41.57000
Density:1.12
LogP:2.33580
Storage Temp.:2-8°C(protect from light)
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:248.152477885
Heavy Atom Count:18
Complexity:259

Purity/Quality:

97% ^*data from raw suppliers

benzylmethyl(piperidin-4-yl)carbamate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C1CCNCC1)C(=O)OCC2=CC=CC=C2

Technology Process of Benzyl methyl(piperidin-4-yl)carbamate

There total 6 articles about Benzyl methyl(piperidin-4-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 847039-05-8
4-(((benzyloxy)carbonyl)(methyl)amino)piperidine-1-carboxylic acid tert-butyl ester

: 553672-39-2
benzyl N-methyl-N-(4-piperidyl)carbamate

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 - 25 ℃; for 1h;

Reference yield:

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 553672-39-2
benzyl N-methyl-N-(4-piperidyl)carbamate

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid / methanol / 2 h / 20 °C

1.2: 14 h / 0 - 20 °C

2.1: potassium carbonate / dichloromethane / 14 h / 20 °C

3.1: trifluoroacetic acid / dichloromethane / 2 h / 0 - 20 °C

With potassium carbonate; trifluoroacetic acid; acetic acid; In methanol; dichloromethane;

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 553672-39-2
benzyl N-methyl-N-(4-piperidyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / tetrahydrofuran / 3 h / 0 - 20 °C

2: trifluoroacetic acid / dichloromethane / 3 h / 0 °C

With sodium carbonate; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1021/acs.jmedchem.8b00794