6-bromo-2H-chromene-3-carboxylic acid

Base Information

Chemical Name:6-bromo-2H-chromene-3-carboxylic acid
CAS No.:380607-15-8
Molecular Formula:C₁₀H₇BrO₃
Molecular Weight:255.068
Hs Code.:2916190090
DSSTox Substance ID:DTXSID00585443
Nikkaji Number:J3.513.697E
Wikidata:Q82477412
Mol file:380607-15-8.mol

Synonyms:6-bromo-2H-chromene-3-carboxylic acid;380607-15-8;6-Bromo-2H-chromene-3-carboxylicacid;6-bromo-2H-1-benzopyran-3-carboxylic acid;SCHEMBL416748;AMY6529;DTXSID00585443;NXMIFPOLKMLPLG-UHFFFAOYSA-N;MFCD04035698;AKOS001325044;AB16979;TS-03442;CS-0215620;EN300-26717;A823999;F2121-0013;Z228460232

Suppliers and Price of 6-bromo-2H-chromene-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
6-Bromo-2H-chromene-3-carboxylicacid 95%
5 g
$ 495.00

SynQuest Laboratories
6-Bromo-2H-chromene-3-carboxylicacid 95%
250 mg
$ 75.00

SynQuest Laboratories
6-Bromo-2H-chromene-3-carboxylicacid 95%
1 g
$ 175.00

Matrix Scientific
6-Bromo-2H-chromene-3-carboxylic acid 97%
1g
$ 323.00

J&W Pharmlab
6-Bromo-2H-chromene-3-carboxylicacid 96%
1g
$ 130.00

Crysdot
6-Bromo-2H-chromene-3-carboxylicacid 95+%
5g
$ 560.00

Crysdot
6-Bromo-2H-chromene-3-carboxylicacid 95+%
1g
$ 260.00

Chemenu
6-Bromo-2H-chromene-3-carboxylicacid 95%
5g
$ 337.00

Apolloscientific
6-Bromo-2H-chromene-3-carboxylicacid
1g
$ 131.00

Apolloscientific
6-Bromo-2H-chromene-3-carboxylicacid
250mg
$ 44.00

Total 10 raw suppliers

Chemical Property of 6-bromo-2H-chromene-3-carboxylic acid

Chemical Property:

Boiling Point:380.5±42.0 °C(Predicted)
PKA:3.54±0.20(Predicted)
PSA：46.53000
Density:1.734±0.06 g/cm3(Predicted)
LogP:2.30950
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:253.95786
Heavy Atom Count:14
Complexity:275

Purity/Quality:

97% ^*data from raw suppliers

6-Bromo-2H-chromene-3-carboxylicacid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=CC2=C(O1)C=CC(=C2)Br)C(=O)O

Technology Process of 6-bromo-2H-chromene-3-carboxylic acid

There total 3 articles about 6-bromo-2H-chromene-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.4%

: 548756-58-7
tert-butyl 3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-2-methylenenpropanoate

: 380607-15-8
6-bromo-2H-chromene-3-carboxylic acid

Guidance literature:: With potassium hydroxide; In water; for 42h; Reflux;
DOI:10.1016/j.tet.2015.04.104

Reference yield: 59.0%

: 57543-68-7
6‐bromo‐2H‐chromene‐3‐carbonitrile

: 380607-15-8
6-bromo-2H-chromene-3-carboxylic acid

Guidance literature:: 6‐bromo‐2H‐chromene‐3‐carbonitrile; With water; sodium hydroxide; for 6h; Reflux;

With hydrogenchloride; In water;

Reference yield:

: 1761-61-1
5-bromosalicyclaldehyde

: 380607-15-8
6-bromo-2H-chromene-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1,4-diaza-bicyclo[2.2.2]octane / Reflux

2: sodium hydroxide; water / 6 h / Reflux

With water; sodium hydroxide; 1,4-diaza-bicyclo[2.2.2]octane;