Digoxigenin NHS ester

Base Information

• Chemical Name: Digoxigenin NHS ester
• CAS No.: 129273-26-3
• Molecular Formula: C35H50N2O10
• Molecular Weight: 658.784
• European Community (EC) Number: 635-044-5
• Mol file: 129273-26-3.mol

Synonyms:HDMA;N-hydroxysuccinimidyl digoxigenin-3-O-methylcarbonyl-epsilon-aminocaproate

Chemical Property of Digoxigenin NHS ester

Chemical Property:

• Density: 1.33g/cm³
• Storage Temp.: −20°C
• Solubility.: DMF: soluble
• XLogP3: 1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 12
• Exact Mass: 658.34654580
• Heavy Atom Count: 47
• Complexity: 1300

Purity/Quality:

98%,99%, ^*data from raw suppliers

Digoxigenin NHS-ester ≥80%(HPLC) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T+
• Statements: 26/27/28-33
• Safety Statements: 28-36/37-45

MSDS Files:

Useful:

• Canonical SMILES: CC12CCC(CC1CCC3C2CC(C4(C3(CCC4C5=CC(=O)OC5)O)C)O)OCC(=O)NCCCCCC(=O)ON6C(=O)CCC6=O
• Isomeric SMILES: C[C@]12CC[C@@H](C[C@H]1CC[C@@H]3[C@@H]2C[C@H]([C@]4([C@@]3(CC[C@@H]4C5=CC(=O)OC5)O)C)O)OCC(=O)NCCCCCC(=O)ON6C(=O)CCC6=O
• Uses: Digoxigenin NHS-ester is an activated ester which reacts with amino groups under mild conditions, attaching the digoxigenin moiety to proteins or 5′-amino substituted oligonucleotides Digoxigenin labeling is used to immuno-tag molecules for detection using anti-digoxigenin antibodies with high affinities and specificity. Digoxigenin-3-O-methylcarbonyl-ε-aminocaproic acid-N-hydroxysuccinimide ester has been used to label the sequence (III) for the linker molecule sequence (VIII).