3-Formyl-1H-indole-2-carboxylic acid

Base Information

Chemical Name:3-Formyl-1H-indole-2-carboxylic acid
CAS No.:28737-34-0
Molecular Formula:C10H7NO3
Molecular Weight:189.17
Hs Code.:2933990090
ChEMBL ID:CHEMBL23953
DSSTox Substance ID:DTXSID501288945
Nikkaji Number:J377.457K
Mol file:28737-34-0.mol

Synonyms:3-Formyl-1H-indole-2-carboxylic acid;28737-34-0;MFCD06809647;1H-Indole-2-carboxylic acid, 3-formyl-;3-formyl-indole-2-carboxylic;CHEMBL23953;SCHEMBL5008079;PRFDLSPESODVAW-UHFFFAOYSA-N;DTXSID501288945;3-Formyl-1H-indole-2-carboxylicacid;AKOS001763298;SY089449;VS-07193;CS-0182626;E78448;EN300-142673;Z1198171577

Suppliers and Price of 3-Formyl-1H-indole-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Formyl-1H-indole-2-carboxylicAcid
250mg
$ 310.00

Matrix Scientific
3-Formyl-1H-indole-2-carboxylic acid
1g
$ 235.00

Crysdot
3-Formyl-1H-indole-2-carboxylicacid 95+%
5g
$ 662.00

Chemenu
3-Formyl-1H-indole-2-carboxylicacid 95%
5g
$ 626.00

American Custom Chemicals Corporation
3-FORMYL-1H-INDOLE-2-CARBOXYLIC ACID 95.00%
10G
$ 2483.25

American Custom Chemicals Corporation
3-FORMYL-1H-INDOLE-2-CARBOXYLIC ACID 95.00%
5G
$ 1697.85

American Custom Chemicals Corporation
3-FORMYL-1H-INDOLE-2-CARBOXYLIC ACID 95.00%
1G
$ 1062.60

AK Scientific
3-Formyl-1H-indole-2-carboxylicacid
1g
$ 367.00

Total 8 raw suppliers

Chemical Property of 3-Formyl-1H-indole-2-carboxylic acid

Chemical Property:

Melting Point:238 °C
Boiling Point:481.5±30.0 °C(Predicted)
PKA:4.81±0.30(Predicted)
PSA：70.16000
Density:1.500±0.06 g/cm3(Predicted)
LogP:1.67860
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:189.042593085
Heavy Atom Count:14
Complexity:254

Purity/Quality:

97% ^*data from raw suppliers

3-Formyl-1H-indole-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=C(N2)C(=O)O)C=O

Technology Process of 3-Formyl-1H-indole-2-carboxylic acid

There total 5 articles about 3-Formyl-1H-indole-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 18450-27-6
ethyl 3-formyl-1H-indole-2-carboxylate

: 28737-34-0
3-formyl-indole-2-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol;
DOI:10.1016/0223-5234(96)88316-4

Reference yield:

: 18450-26-5
methyl 3-formyl-1H-indole-2-carboxylate

: 28737-34-0
3-formyl-indole-2-carboxylic acid

Guidance literature:: With water; potassium hydroxide; In ethanol; at 20 ℃; for 3h;
DOI:10.1080/00397911.2020.1786124

Reference yield:

: 3770-50-1,117770-52-2
2-carbethoxyindole

: 28737-34-0
3-formyl-indole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) POCl₃ / 2) 40-60 deg C, 4 h

2: 82 percent / aq. KOH / ethanol

With potassium hydroxide; trichlorophosphate; In ethanol;
DOI:10.1016/0223-5234(96)88316-4