ethyl 4-oxo-5,10-dihydro-4H-benzo[e]pyrazolo[1,5-a][1,4]diazepine-2-carboxylate

Base Information

Chemical Name:ethyl 4-oxo-5,10-dihydro-4H-benzo[e]pyrazolo[1,5-a][1,4]diazepine-2-carboxylate
CAS No.:87592-06-1
Molecular Formula:C₁₂H₉N₃O₃
Molecular Weight:243.222
Hs Code.:
Mol file:87592-06-1.mol

Synonyms:ethyl 4-oxo-5,10-dihydro-4H-benzo[e]pyrazolo[1,5-a][1,4]diazepine-2-carboxylate;9-methyl-4-oxo-5,10-dihydro-4H-benzo[e]pyrazolo[1,5-a][1,4]diazepine-2-carboxylic acid

Suppliers and Price of ethyl 4-oxo-5,10-dihydro-4H-benzo[e]pyrazolo[1,5-a][1,4]diazepine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 4 raw suppliers

Chemical Property of ethyl 4-oxo-5,10-dihydro-4H-benzo[e]pyrazolo[1,5-a][1,4]diazepine-2-carboxylate

Chemical Property:

PSA：84.22000
LogP:1.33330

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ethyl 4-oxo-5,10-dihydro-4H-benzo[e]pyrazolo[1,5-a][1,4]diazepine-2-carboxylate

There total 5 articles about ethyl 4-oxo-5,10-dihydro-4H-benzo[e]pyrazolo[1,5-a][1,4]diazepine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 87592-05-0
methyl 5,10-dihydro-11-oxopyrazolo<5,1-c><1,4>benzodiazepine-2-carboxylate

: 87592-06-1
5,10-dihydro-11-oxopyrazolo<5,1-c><1,4>benzodiazepine-2-carboxylic acid

Guidance literature:: With hydrogenchloride; In acetic acid; for 0.583333h; Heating;
DOI:10.1002/jhet.5570200407

Reference yield:

: 4077-76-3
3,5-dicarbomethoxypyrazole

: 87592-06-1
5,10-dihydro-11-oxopyrazolo<5,1-c><1,4>benzodiazepine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 1) potassium / 1) THF, reflux, 12 h; 2) reflux, 8 h

2: 85 percent / hydrogen / 10percent Pd/C / ethyl acetate / 5 h / 2585.7 Torr

3: 84 percent / 180 - 200 °C

4: 75 percent / 6N HCl / acetic acid / 0.58 h / Heating

With hydrogenchloride; hydrogen; potassium; palladium on activated charcoal; In acetic acid; ethyl acetate;
DOI:10.1002/jhet.5570200407

Reference yield:

: 87592-00-5
dimethyl 1-(2-nitrobenzyl)pyrazole-3,5-dicarboxylate

: 87592-06-1
5,10-dihydro-11-oxopyrazolo<5,1-c><1,4>benzodiazepine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / hydrogen / 10percent Pd/C / ethyl acetate / 5 h / 2585.7 Torr

2: 84 percent / 180 - 200 °C

3: 75 percent / 6N HCl / acetic acid / 0.58 h / Heating

With hydrogenchloride; hydrogen; palladium on activated charcoal; In acetic acid; ethyl acetate;
DOI:10.1002/jhet.5570200407