4-Epi-6-epi Doxycycline

Base Information

• Chemical Name: 4-Epi-6-epi Doxycycline
• CAS No.: 97583-08-9
• Molecular Formula: C₂₂H₂₄N₂O₈
• Molecular Weight: 444.441
• Mol file: 97583-08-9.mol

Synonyms:4-Epi-6-epi Doxycycline;(4R,4aR,5S,5aR,6S,12aS)-4-(DiMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-Methyl-1,11-dioxo-2-naphthacenecarboxaMide;[4R-(4α,4aβ,5β,5aβ,6α,12aβ)]-4-(DiMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-Methyl-1,11-dioxo-2-naphthacenecarboxaMide;4-Epi-6-epi Doxycycline Discontinued

Chemical Property of 4-Epi-6-epi Doxycycline

Chemical Property:

• Boiling Point: 762.6±60.0 °C(Predicted)
• PKA: 4.50±1.00(Predicted)
• PSA: 182.61000
• Density: 1.63±0.1 g/cm3(Predicted)
• LogP: 0.80210

Purity/Quality:

≥95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-Epi-6-epi Doxycycline is an impurity of Doxycycline (D561500).

Technology Process of 4-Epi-6-epi Doxycycline

There total 2 articles about 4-Epi-6-epi Doxycycline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-epi-6-Desoxy-5-hydroxy-tetracyclin (564-25-0,3219-99-6,6543-77-7,22775-54-8,60080-38-8,97583-08-9,10597-92-9,7164-70-7,7264-10-0)

Guidance literature:

6-Desoxy-5-hydroxy-tetracyclin, wss.-methanol. NaH2PO4, N2-Atm., 24h, 25grad; als Gleichgew.-Gemisch;

DOI:10.1021/ja01498a037

Reference yield:

→ 6-Epi-6-desoxy-5-oxytetracyclin (564-25-0,3219-99-6,6543-77-7,22775-54-8,60080-38-8,97583-08-9,10597-92-9,7164-70-7,7264-10-0)

Guidance literature:

6-Desoxy-6-desmethyl-6-methylen-5-oxytetracyclin, 1.) H2, Rh/C, 2.) Trennung ueber Sulfosalicylsaeuresalze;