Chlorthalidone

Base Information

• Chemical Name: Chlorthalidone
• CAS No.: 74666-82-3
• Molecular Formula: C₁₄H₁₁ClN₂O₄S
• Molecular Weight: 338.771
• Mol file: 74666-82-3.mol

Synonyms:Chlorthalidone;2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)-benzenesulfonamide;

Chemical Property of Chlorthalidone

Chemical Property:

• PSA: 117.87000
• LogP: 3.03410

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Chlorthalidone

There total 2 articles about Chlorthalidone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chlorthalidon (77-36-1) → (+)-Chlortalidon (77-36-1,74658-80-3,74658-81-4,74666-82-3) + (-)-Chlortalidon (77-36-1,74658-80-3,74658-81-4,74666-82-3)

Guidance literature:

Yield given. Yields of byproduct given;

DOI:10.1002/cber.19801130538

Reference yield:

chlorthalidon (77-36-1) → (+)-Chlortalidon (77-36-1,74658-80-3,74658-81-4,74666-82-3) + (-)-Chlortalidon (77-36-1,74658-80-3,74658-81-4,74666-82-3)

Guidance literature:

Yield given. Yields of byproduct given;

DOI:10.1002/cber.19801130538

Reference yield:

(-)-Chlortalidon (77-36-1,74658-80-3,74658-81-4,74666-82-3) → chlorthalidon (77-36-1)

Guidance literature:

With buffer solution; In 1,4-dioxane; half time of racemization;

DOI:10.1002/cber.19801130538

upstream raw materials:

chlorthalidon

Downstream raw materials:

chlorthalidon

Refernces