2-Phenyltetrahydrofuran-2-carboxylic acid

Base Information

Chemical Name:2-Phenyltetrahydrofuran-2-carboxylic acid
CAS No.:19679-84-6
Molecular Formula:C₁₁H₁₂O₃
Molecular Weight:192.214
Hs Code.:
European Community (EC) Number:855-287-2
Mol file:19679-84-6.mol

Synonyms:19679-84-6;2-phenyltetrahydrofuran-2-carboxylic acid;2-phenyloxolane-2-carboxylic acid;Tetrahydro-2-phenyl-2-furancarboxylic acid;2-Phenyl-2-tetrahydrofuroic Acid;SCHEMBL4829823;XYCFRUQFTPLHSD-UHFFFAOYSA-N;2-phenyltetrahydrofuran-2-carboxylicacid;DA-08606;E73375;EN300-705664

Suppliers and Price of 2-Phenyltetrahydrofuran-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
2-Phenyl-2-tetrahydrofuroicAcid
10g
$ 4492.00

AK Scientific
2-Phenyl-2-tetrahydrofuroicAcid
1g
$ 1121.00

Total 3 raw suppliers

Chemical Property of 2-Phenyltetrahydrofuran-2-carboxylic acid

Chemical Property:

PSA：46.53000
LogP:1.77690
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:192.078644241
Heavy Atom Count:14
Complexity:221

Purity/Quality:

99% ^*data from raw suppliers

2-Phenyl-2-tetrahydrofuroicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(OC1)(C2=CC=CC=C2)C(=O)O

Technology Process of 2-Phenyltetrahydrofuran-2-carboxylic acid

There total 2 articles about 2-Phenyltetrahydrofuran-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 10413-00-0
5-oxo-5-phenylpentanenitrile

: 19679-84-6
2-phenyl-tetrahydro-furan-2-carboxylic acid

Guidance literature:: With potassium hydroxide; ethylene glycol; at 200 ℃;
DOI:10.1016/S0960-894X(02)00211-1

Reference yield:

: 939-52-6
4-chloro-1-phenylbutan-1-one

: 19679-84-6
2-phenyl-tetrahydro-furan-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: methanol

2: KOH; ethylene glycol / 200 °C

With potassium hydroxide; ethylene glycol; In methanol;
DOI:10.1016/S0960-894X(02)00211-1

Reference yield:

: 19679-84-6
2-phenyl-tetrahydro-furan-2-carboxylic acid

: (S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[((S)-2-phenyl-tetrahydro-furan-2-carbonyl)-amino]-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: PyBOP; DIPEA / CH₂Cl₂

2: TFA / CH₂Cl₂

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/S0960-894X(02)00211-1