2,6-Bis(2-bromo-5-methoxybenzyl)cyclohexanone

Base Information

Chemical Name:2,6-Bis(2-bromo-5-methoxybenzyl)cyclohexanone
CAS No.:815610-54-9
Molecular Formula:C₂₂H₂₄Br₂O₃
Molecular Weight:496.239
Hs Code.:
DSSTox Substance ID:DTXSID30697083
Nikkaji Number:J2.116.866A

Synonyms:2,6-BIS(2-BROMO-5-METHOXYBENZYL)CYCLOHEXANONE;815610-54-9;SCHEMBL19050170;DTXSID30697083;2,6-Bis[(2-bromo-5-methoxyphenyl)methyl]cyclohexan-1-one

Suppliers and Price of 2,6-Bis(2-bromo-5-methoxybenzyl)cyclohexanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2,6-Bis(2-bromo-5-methoxybenzyl)cyclohexanone

Chemical Property:

XLogP3:6.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:496.00717
Heavy Atom Count:27
Complexity:446

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)Br)CC2CCCC(C2=O)CC3=C(C=CC(=C3)OC)Br

Technology Process of 2,6-Bis(2-bromo-5-methoxybenzyl)cyclohexanone

There total 4 articles about 2,6-Bis(2-bromo-5-methoxybenzyl)cyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 815610-53-8
2,6-bis(3-methoxybenzyl)cyclohexan-1-one

: 815610-54-9
2,6-bis(2-bromo-5-methoxybenzyl)cyclohexan-1-one

Guidance literature:: With pyridine; bromine; In dichloromethane; at -10 - 20 ℃;
DOI:10.1016/j.tetasy.2004.09.016

Reference yield:

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 815610-54-9
2,6-bis(2-bromo-5-methoxybenzyl)cyclohexan-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: NaOH / aq. ethanol / 4.5 h / 20 °C

2: 78 percent / H₂ / Raney nickel / acetone / 12 h / 20 °C

3: pyridine; Br₂ / CH₂Cl₂ / -10 - 20 °C

With pyridine; sodium hydroxide; hydrogen; bromine; nickel; In ethanol; dichloromethane; acetone;
DOI:10.1016/j.tetasy.2004.09.016

Reference yield:

: 591-31-1
3-methoxy-benzaldehyde

: 815610-54-9
2,6-bis(2-bromo-5-methoxybenzyl)cyclohexan-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: NaOH / aq. ethanol / 4.5 h / 20 °C

2: 78 percent / H₂ / Raney nickel / acetone / 12 h / 20 °C

3: pyridine; Br₂ / CH₂Cl₂ / -10 - 20 °C

With pyridine; sodium hydroxide; hydrogen; bromine; nickel; In ethanol; dichloromethane; acetone;
DOI:10.1016/j.tetasy.2004.09.016