diphenyl(4-(trifluoroMethoxy)phenyl)phosphine oxide

Base Information

• Chemical Name: diphenyl(4-(trifluoroMethoxy)phenyl)phosphine oxide
• CAS No.: 1448632-02-7
• Molecular Formula: C19H14F3O2P
• Molecular Weight: 362.288
• Mol file: 1448632-02-7.mol

Synonyms:diphenyl(4-(trifluoroMethoxy)phenyl)phosphine oxide

Chemical Property of diphenyl(4-(trifluoroMethoxy)phenyl)phosphine oxide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of diphenyl(4-(trifluoroMethoxy)phenyl)phosphine oxide

There total 8 articles about diphenyl(4-(trifluoroMethoxy)phenyl)phosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

Diphenylphosphine oxide (4559-70-0) + 4-trifluoromethoxyphenylboronic acid (139301-27-2) → diphenyl (4-(trifluoromethoxy)phenyl)phosphine oxide (1448632-02-7)

Guidance literature:

With palladium diacetate; potassium carbonate; 1,4-di(diphenylphosphino)-butane; In 1,4-dioxane; at 90 ℃; for 24h; Green chemistry;

DOI:10.1039/c3ob42470g

Reference yield: 90.0%

bis(4-(trifluoromethoxy)phenyl)iodonium tetrafluoroborate (1448631-97-7) + Diphenylphosphine oxide (4559-70-0) → diphenyl (4-(trifluoromethoxy)phenyl)phosphine oxide (1448632-02-7)

Guidance literature:

With triethylamine; copper(l) chloride; In dichloromethane; at 20 ℃; for 0.166667h; Schlenk technique;

DOI:10.1021/jo4012199

Reference yield: 81.0%

1-chloro-4-(trifluoromethoxy)benzene (461-81-4) + Diphenylphosphine oxide (4559-70-0) → diphenyl (4-(trifluoromethoxy)phenyl)phosphine oxide (1448632-02-7)

Guidance literature:

With Sodium hydrogenocarbonate; In acetonitrile; at 20 ℃; for 24h; Irradiation;

DOI:10.1002/cctc.202200449

upstream raw materials:

bis(4-(trifluoromethoxy)phenyl)iodonium tetrafluoroborate

Diphenylphosphine oxide

4-trifluoromethoxyphenylboronic acid

Triphenylphosphine oxide