4-Amino-5-bromo-2-ethoxybenzoic acid

Base Information

Chemical Name:4-Amino-5-bromo-2-ethoxybenzoic acid
CAS No.:84923-73-9
Molecular Formula:C9H10BrNO3
Molecular Weight:260.0846
Hs Code.:
DSSTox Substance ID:DTXSID20455518
Wikidata:Q82277574

Synonyms:4-Amino-5-bromo-2-ethoxybenzoic acid;84923-73-9;SCHEMBL1502096;DTXSID20455518;4-Amino-5-bromo-2-ethoxybenzoicacid

Suppliers and Price of 4-Amino-5-bromo-2-ethoxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-Amino-5-bromo-2-ethoxybenzoic acid

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:258.98441
Heavy Atom Count:14
Complexity:212

Purity/Quality:: ≥99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC(=C(C=C1C(=O)O)Br)N

Technology Process of 4-Amino-5-bromo-2-ethoxybenzoic acid

There total 3 articles about 4-Amino-5-bromo-2-ethoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 483304-07-0
methyl 4-acetylamino-5-bromo-2-ethoxybenzoate

: 84923-73-9
4-amino-5-bromo-2-ethoxybenzoic acid

Guidance literature:: With sodium hydroxide; In methanol; for 4h; Heating;
DOI:10.1248/cpb.50.941

Reference yield:

: 59-06-3
methyl 4-acetamido-2-ethoxybenzoate

: 84923-73-9
4-amino-5-bromo-2-ethoxybenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / NBS / dimethylformamide / 3.5 h / 80 °C

2: 98 percent / aq. NaOH / methanol / 4 h / Heating

With sodium hydroxide; N-Bromosuccinimide; In methanol; N,N-dimethyl-formamide;
DOI:10.1248/cpb.50.941

Reference yield:

: 4136-97-4
methyl 4-aminosalicylate

: 84923-73-9
4-amino-5-bromo-2-ethoxybenzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: acetic acid / 1 h

2: sodium hydroxide / N,N-dimethyl-formamide

3: N-Bromosuccinimide / N,N-dimethyl-formamide

4: sodium hydroxide / ethanol

With N-Bromosuccinimide; acetic acid; sodium hydroxide; In ethanol; N,N-dimethyl-formamide;
DOI:10.2174/157018012800389386