ent-11,16-Epoxy-15-hydroxykauran-19-oic acid

Base Information

• Chemical Name: ent-11,16-Epoxy-15-hydroxykauran-19-oic acid
• CAS No.: 77658-46-9
• Molecular Formula: C₂₀H₃₀O₄
• Molecular Weight: 334.456
• Mol file: 77658-46-9.mol

Synonyms:ent-11,16-Epoxy-15-hydroxykauran-19-oic acid;(4alpha,11beta,15beta,16alpha)-11,16-Epoxy-15-hydroxykauran-18-oic acid

Chemical Property of ent-11,16-Epoxy-15-hydroxykauran-19-oic acid

Chemical Property:

• PSA: 66.76000
• LogP: 3.22210

Purity/Quality:

98% ^*data from raw suppliers

ent-11,16-Epoxy-15-hydroxykauran-19-oicacid ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ent-11,16-Epoxy-15-hydroxykauran-19-oic acid

There total 1 articles about ent-11,16-Epoxy-15-hydroxykauran-19-oic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ent-11α,15α-dihydroxy-kaur-16-en-19-saeure (57719-76-3,71135-30-3) → ent-11α,16α-epoxy-15α-hydroxy-16S-kauran-19-saeure (77658-46-9)

Guidance literature:

With hydrogenchloride; In methanol; diethyl ether; at 0 ℃; for 24h;

DOI:10.1248/cpb.29.657

Reference yield:

ent-11α,16α-epoxy-15α-hydroxy-16S-kauran-19-saeure (77658-46-9) → ent-11α,16α-epoxy-16R-kauran-19-saeure (77658-36-7)

Guidance literature:

Multi-step reaction with 2 steps

1: Jones reagent / acetone / 0.5 h

2: hydrazine hydrate, KOH / ethanol; bis-(2-hydroxy-ethyl) ether / reflux 1 h, then 230 deg C, 4 h

With potassium hydroxide; jones reagent; hydrazine hydrate; In ethanol; acetone; diethylene glycol;

DOI:10.1248/cpb.29.657

upstream raw materials:

ent-11α,15α-dihydroxy-kaur-16-en-19-saeure

Downstream raw materials:

ent-11α,16α-epoxy-16R-kauran-19-saeure