Tetraisopropyl Fluoromethylenediphosphonate

Base Information

Chemical Name:Tetraisopropyl Fluoromethylenediphosphonate
CAS No.:78715-57-8
Molecular Formula:C₁₃H₂₉FO₆P₂
Molecular Weight:362.316
Hs Code.:
DSSTox Substance ID:DTXSID30508105
Nikkaji Number:J2.277.209K
Wikidata:Q82364812
Mol file:78715-57-8.mol

Synonyms:Tetraisopropyl Fluoromethylenediphosphonate;78715-57-8;2-[[di(propan-2-yloxy)phosphoryl-fluoromethyl]-propan-2-yloxyphosphoryl]oxypropane;Tetraisopropyl (fluoromethylene)bis(phosphonate);starbld0002900;Tetrapropan-2-yl (fluoromethylene)bis(phosphonate);SCHEMBL3437015;DTXSID30508105;XXNLZMODXBPUOM-UHFFFAOYSA-N;AKOS030240543;FT-0675077;tetraisopropyl monofluoromethylenediphosphonate;[(Diisopropoxy-phosphoryl)-fluoro-methyl]-phosphonic acid diisopropyl ester

Suppliers and Price of Tetraisopropyl Fluoromethylenediphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Tetraisopropyl Fluoromethylenediphosphonate
10mg
$ 446.00

TRC
TetraisopropylFluoromethylenediphosphonate
100mg
$ 1230.00

TRC
TetraisopropylFluoromethylenediphosphonate
10mg
$ 155.00

Total 6 raw suppliers

Chemical Property of Tetraisopropyl Fluoromethylenediphosphonate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:394.102°C at 760 mmHg
Flash Point:192.146°C
PSA：90.68000
Density:1.118g/cm³
LogP:5.32570
Solubility.:Ethyl acetate, Methanol
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:10
Exact Mass:362.14234080
Heavy Atom Count:22
Complexity:359

Purity/Quality:

97% ^*data from raw suppliers

Tetraisopropyl Fluoromethylenediphosphonate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)OP(=O)(C(F)P(=O)(OC(C)C)OC(C)C)OC(C)C
Uses An intermediate for the synthesis of 5’-diphosphate and 5’-triphosphate mimics for transcriptase inhibition.

Technology Process of Tetraisopropyl Fluoromethylenediphosphonate

There total 3 articles about Tetraisopropyl Fluoromethylenediphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 1660-95-3
Tetraisopropyl methylenediphosphonate

: 78715-57-8
fluoromethylenebisphosphonic acid tetraisopropyl ester

: 78715-59-0
tetraisopropyl (difluoromethylene)bisphosphonate

Guidance literature:: Tetraisopropyl methylenediphosphonate; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1.41667h;

With Selectfluor; In N,N-dimethyl-formamide; at 0 - 20 ℃;
DOI:10.1021/jo0518598

Reference yield: 13.0%

: 1660-95-3
Tetraisopropyl methylenediphosphonate

: 681-80-1
diisopropyl difluoromethanephosphonate

: 78715-57-8
fluoromethylenebisphosphonic acid tetraisopropyl ester

: 78715-59-0
tetraisopropyl (difluoromethylene)bisphosphonate

Guidance literature:: With perchloryl fluoride; potassium tert-butylate; In toluene; for 0.833333h; temperature below 22 deg C;
DOI:10.1021/jo00335a053