2-(4-tert-Butylbenzoyl)cyclohexanecarboxylic acid

Base Information

• Chemical Name: 2-(4-tert-Butylbenzoyl)cyclohexanecarboxylic acid
• CAS No.: 72987-29-2
• Molecular Formula: C₁₈H₂₄O₃
• Molecular Weight: 288.387
• Mol file: 72987-29-2.mol

Synonyms:2-(4-tert-Butylbenzoyl)cyclohexanecarboxylic acid;2-[4-(1,1-Dimethylethyl)benzoyl]cyclohexanecarboxylic acid

Chemical Property of 2-(4-tert-Butylbenzoyl)cyclohexanecarboxylic acid

Chemical Property:

Purity/Quality:

2-(4-tert-Butyl-benzoyl)-cyclohexanecarboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-tert-Butylbenzoyl)cyclohexanecarboxylic acid

There total 1 articles about 2-(4-tert-Butylbenzoyl)cyclohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-tert-butylphenyl triflate (154318-75-9) + 1,2-cis-cyclohexanedicarboxylic anhydride (13149-00-3) → cis-2-(4-(tert-butyl)benzoyl)cyclohexane-1-carboxylic acid (72987-29-2)

Guidance literature:

With [2,2]bipyridinyl; bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; chloro-trimethyl-silane; zinc(II) iodide; zinc; In N,N-dimethyl acetamide; at 80 ℃; for 12h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.8b00114

upstream raw materials:

4-tert-butylphenyl triflate

1,2-cis-cyclohexanedicarboxylic anhydride

Refernces