2-(4-Bromophenyl)cyclopropanecarboxylic acid

Base Information

• Chemical Name: 2-(4-Bromophenyl)cyclopropanecarboxylic acid
• CAS No.: 77255-26-6
• Molecular Formula: C10H9BrO2
• Molecular Weight: 241.084
• Hs Code.: 2916399090
• Mol file: 77255-26-6.mol

Synonyms:2-(4-Bromophenyl)-1-cyclopropanecarboxylic acid

Chemical Property of 2-(4-Bromophenyl)cyclopropanecarboxylic acid

Chemical Property:

• Melting Point: 122 °C
• Boiling Point: 364.5±42.0 °C(Predicted)
• PKA: 4.53±0.10(Predicted)
• PSA: 37.30000
• Density: 1.652±0.06 g/cm3(Predicted)
• LogP: 2.63720
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

2-(4-Bromophenyl)cyclopropane-1-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-Bromophenyl)cyclopropanecarboxylic acid

There total 20 articles about 2-(4-Bromophenyl)cyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethyl trans-2-(p-bromophenyl)-1-cyclopropanecarboxylate (53582-00-6,70461-61-9,91843-55-9) → trans-(1S,2S)/(1R,2R)-2-(4-bromophenyl)cyclopropanecarboxylic acid (6142-65-0,31501-85-6,77255-26-6,2137065-16-6)

Guidance literature:

ethyl trans-2-(p-bromophenyl)-1-cyclopropanecarboxylate; With sodium hydroxide; In ethanol; at 20 ℃; Inert atmosphere;

With hydrogenchloride; In water; at 0 ℃; Inert atmosphere;

DOI:10.1039/c5ob02577j

Reference yield: 100.0%

→ trans-2-(4-bromophenyl)cyclopropanecarboxylic acid (77255-26-6,2137065-16-6)

Guidance literature:

With methanol; sodium hydroxide;

Reference yield: 99.0%

tert-butyl 2-(4-bromophenyl)cyclopropanecarboxylate (1366440-18-7) → trans-2-(4-bromophenyl)cyclopropanecarboxylic acid (77255-26-6,2137065-16-6)

Guidance literature:

tert-butyl 2-(4-bromophenyl)cyclopropanecarboxylate; With water; lithium hydroxide; In tetrahydrofuran; methanol; at 50 - 65 ℃; for 3h;

With hydrogenchloride; In tetrahydrofuran; methanol; water; at 20 ℃; for 0.5h; pH=< 2;

upstream raw materials:

(cis)-2-(4-bromophenyl)cyclopropanecarboxylic acid

1,4-bromoiodobenzene

cyclopropanecarboxylic acid

ethyl trans-2-(p-bromophenyl)-1-cyclopropanecarboxylate

Downstream raw materials:

(1S,2S)-2-(4-bromophenyl)cyclopropanecarboxylic acid

(R,R)-2-(4-bromophenyl)cyclopropanecarboxylic acid

C₁₀H₉BrO₂*C₁₂H₁₃N

4-{(1S, 2S)-2-[((R)-4-cyclobutyl-2-methylpiperazin-1-yl)carbonyl]-cyclopropyl}-benzamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 77255-26-6 2-(4-Bromophenyl)cyclopropanecarboxylic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send