(2E)-3-(4-tert-butylphenyl)acryloyl chloride

Base Information

• Chemical Name: (2E)-3-(4-tert-butylphenyl)acryloyl chloride
• CAS No.: 176690-89-4
• Molecular Formula: C₁₃H₁₅ClO
• Molecular Weight: 222.715
• Hs Code.: 2916399090
• Mol file: 176690-89-4.mol

Synonyms:(2E)-3-(4-tert-butylphenyl)acryloyl chloride;2-propenoyl chloride, 3-[4-(1,1-dimethylethyl)phenyl]-, (2

Chemical Property of (2E)-3-(4-tert-butylphenyl)acryloyl chloride

Chemical Property:

• Boiling Point: 302.5±11.0 °C(Predicted)
• PSA: 17.07000
• Density: 1.083±0.06 g/cm3(Predicted)
• LogP: 3.76270

Purity/Quality:

98%min ^*data from raw suppliers

(2E)-3-(4-tert-butylphenyl)acryloylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2E)-3-(4-tert-butylphenyl)acryloyl chloride

There total 7 articles about (2E)-3-(4-tert-butylphenyl)acryloyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-tert-butyl-trans-cinnamic acid (1208-65-7) → (E)-3-(4-(tert-butyl)phenyl)acryloyl chloride (78974-03-5,176690-89-4)

Guidance literature:

With oxalyl dichloride; In dichloromethane; at 0 - 20 ℃; for 5h;

DOI:10.1016/j.ejmech.2018.02.054

Reference yield:

3-(4-(tert-butyl)phenyl)acrylic acid (1208-65-7) → (E)-3-(4-tert-Butyl-phenyl)-acryloyl chloride (78974-03-5,176690-89-4)

Guidance literature:

With oxalyl dichloride; In dichloromethane; at 0 ℃;

DOI:10.1016/j.bmcl.2011.11.078

Reference yield:

4-tert-butyl-trans-cinnamic acid (1208-65-7) → (E)-3-(4-tert-Butyl-phenyl)-acryloyl chloride (78974-03-5,176690-89-4)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃;

DOI:10.1002/cmdc.201600298

upstream raw materials:

4-tert-Butylbenzaldehyde

3-(4-(tert-butyl)phenyl)acrylic acid

ethyl 3-(4-t-butylphenyl) propenoate

4-tert-butyl-trans-cinnamic acid

Downstream raw materials:

(E)-5-bromo-2-[2-(4-tert-butylphenyl)vinyl]-1H-benzoimidazole