3-chloro-7,8-dihydroisoquinolin-5(6H)-one

Base Information

Chemical Name:3-chloro-7,8-dihydroisoquinolin-5(6H)-one
CAS No.:1105662-39-2
Molecular Formula:C9H8ClNO
Molecular Weight:181.622
Hs Code.:
Mol file:1105662-39-2.mol

Synonyms:3-chloro-7,8-dihydroisoquinolin-5(6H)-one;3-Chloro-7,8-dihydro-5(6H)-isoquinolinone

Suppliers and Price of 3-chloro-7,8-dihydroisoquinolin-5(6H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Chloro-7,8-dihydroisoquinolin-5(6H)-one
2mg
$ 65.00

TRC
3-Chloro-7,8-dihydroisoquinolin-5(6H)-one
1mg
$ 45.00

AK Scientific
3-Chloro-7,8-dihydroisoquinolin-5(6H)-one
1g
$ 1747.00

Abosyn
3-chloro-7,8-dihydroisoquinolin-5(6H)-one 95%-98%
1g
$ 862.00

Total 8 raw suppliers

Chemical Property of 3-chloro-7,8-dihydroisoquinolin-5(6H)-one

Chemical Property:

PSA：29.96000
LogP:2.25400

Purity/Quality:

97% ^*data from raw suppliers

3-Chloro-7,8-dihydroisoquinolin-5(6H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-chloro-7,8-dihydroisoquinolin-5(6H)-one

There total 5 articles about 3-chloro-7,8-dihydroisoquinolin-5(6H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: (E)-3-chloro-7,8-dihydroisoquinolin-5(6H)-one oxime

: 1105662-39-2
3-chloro-7,8-dihydroisoquinolin-5(6H)-one

Guidance literature:: With hydrogenchloride; In acetone; for 1h; Reflux;

Reference yield: 83.0%

: 1105662-37-0
3-chloro-7,8-dihydro-6H-isoquinolin-5-one oxime

: 1105662-39-2
3-chloro-7,8-dihydroisoquinolin-5(6H)-one

Guidance literature:: 3-chloro-7,8-dihydro-6H-isoquinolin-5-one oxime; With hydrogenchloride; In water; acetone; for 6h; Reflux;

With sodium carbonate; In water; acetone; at 20 ℃; Cooling with ice;

Reference yield:

: 875249-27-7
3-chloro-5,6,7,8-tetrahydroisoquinoline

: 1105662-39-2
3-chloro-7,8-dihydroisoquinolin-5(6H)-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium tert-butylate / tetrahydrofuran / 18 h / 20 °C

1.2: 4 h / 0 - 20 °C

2.1: hydrogenchloride / water; acetone / 6 h / Reflux

2.2: 20 °C / Cooling with ice

With hydrogenchloride; potassium tert-butylate; In tetrahydrofuran; water; acetone;