(+/-)-4-aMino-3,4-dihydro-6-fluoro-spiro[2H-1-benzopyran-2,1'-cyclobutane

Base Information

Chemical Name:(+/-)-4-aMino-3,4-dihydro-6-fluoro-spiro[2H-1-benzopyran-2,1'-cyclobutane
CAS No.:934554-58-2
Molecular Formula:C₁₂H₁₄FNO
Molecular Weight:207.248
Hs Code.:
Mol file:934554-58-2.mol

Synonyms:(+/-)-4-aMino-3,4-dihydro-6-fluoro-spiro[2H-1-benzopyran-2,1'-cyclobutane;6-Fluorospiro[chroman-2,1'-cyclobutan]-4-amine

Suppliers and Price of (+/-)-4-aMino-3,4-dihydro-6-fluoro-spiro[2H-1-benzopyran-2,1'-cyclobutane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Fluorospiro[chroman-2,1'-cyclobutan]-4-amine 95+%
1g
$ 551.00

Chemenu
6-fluorospiro[chromane-2,1''-cyclobutan]-4-amine 95%
1g
$ 520.00

Alichem
6-Fluorospiro[chroman-2,1'-cyclobutan]-4-amine
1g
$ 602.55

Total 6 raw suppliers

Chemical Property of (+/-)-4-aMino-3,4-dihydro-6-fluoro-spiro[2H-1-benzopyran-2,1'-cyclobutane

Chemical Property:

PSA：35.25000
LogP:3.23100

Purity/Quality:

97% ^*data from raw suppliers

6-Fluorospiro[chroman-2,1'-cyclobutan]-4-amine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (+/-)-4-aMino-3,4-dihydro-6-fluoro-spiro[2H-1-benzopyran-2,1'-cyclobutane

There total 3 articles about (+/-)-4-aMino-3,4-dihydro-6-fluoro-spiro[2H-1-benzopyran-2,1'-cyclobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 1144501-14-3
(E)-6-fluorospiro[chroman-2,1'-cyclobutan]-4-one O-methyl oxime

: 934554-58-2,934554-59-3,934554-60-6
6-fluorospiro[chroman-2,1'-cyclobutan]-4-amine

Guidance literature:: With ammonia; hydrogen; Raney nickel, water wet; In ethanol; at 32 ℃; for 3h;

Reference yield:

: 934554-57-1
6-fluorospiro[chroman-2,1'-cyclobutan]-4-one

: 934554-58-2,934554-59-3,934554-60-6
6-fluorospiro[chroman-2,1'-cyclobutan]-4-amine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 54 h / 20 °C

2: hydrogen; ammonia / ethanol / 3 h / 32 °C

With ammonia; hydrogen; In pyridine; ethanol;