2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetamide

Base Information

Chemical Name:2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetamide
CAS No.:101999-45-5
Molecular Formula:C11H9NO4
Molecular Weight:219.19
Hs Code.:2932209090
DSSTox Substance ID:DTXSID80420601
Wikidata:Q82231902
ChEMBL ID:CHEMBL12241
Mol file:101999-45-5.mol

Synonyms:2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetamide;101999-45-5;2-(7-hydroxy-2-oxochromen-4-yl)acetamide;CHEMBL12241;CHEMBRDG-BB 7932577;MFCD06001840;SCHEMBL723839;DTXSID80420601;YXBOCMCJTKIUAP-UHFFFAOYSA-N;HMS1594D16;BDBM50022177;STK829483;AKOS004936952;CS-0210317;2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetamide;SR-01000288598;SR-01000288598-1;4-[(aminocarbonyl)methyl]-7-hydroxy-2H-chromen-2-one;2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)acetamide, AldrichCPR

Suppliers and Price of 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)acetamide
50mg
$ 60.00

TRC
2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)acetamide
10mg
$ 45.00

ChemBridge Corporation
2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetamide 95%
250 mg
$ 44.00

American Custom Chemicals Corporation
2-(7-HYDROXY-2-OXO-2H-CHROMEN-4-YL)ACETAMIDE 95.00%
5MG
$ 503.56

Total 5 raw suppliers

Chemical Property of 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetamide

Chemical Property:

Vapor Pressure:1.27E-12mmHg at 25°C
Boiling Point:548°C at 760 mmHg
Flash Point:285.2°C
PSA：93.53000
Density:1.443g/cm³
LogP:1.22670
XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:219.05315777
Heavy Atom Count:16
Complexity:350

Purity/Quality:

97% ^*data from raw suppliers

2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1O)OC(=O)C=C2CC(=O)N

Technology Process of 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetamide

There total 7 articles about 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 15991-13-6
7-hydroxycoumarin-4-acetic acid methyl ester

: 101999-45-5
2-[7-hydroxy-2-oxo-2H-chromen-4-yl]acetamide

Guidance literature:: With ammonium hydroxide; at 25 ℃;
DOI:10.1021/jm00156a031

Reference yield: 50.0%

: 74083-58-2
(7-hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid ethyl ester

: 101999-45-5
2-[7-hydroxy-2-oxo-2H-chromen-4-yl]acetamide

Guidance literature:: With ammonia; In methanol; at 90 ℃; for 60h;
DOI:10.1021/jm9010127

Reference yield:

: 6950-82-9
2-(7-hydroxy-2-oxochromen-4-yl)acetic acid

: 101999-45-5
2-[7-hydroxy-2-oxo-2H-chromen-4-yl]acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: H⁺

2: aq. NH₃

With ammonium hydroxide; hydrogen cation;
DOI:10.1021/ol062889f