5-Chloro Bupropion FuMarate

Base Information

• Chemical Name: 5-Chloro Bupropion FuMarate
• CAS No.: 1193779-50-8
• Molecular Formula: C17H21Cl2NO5
• Molecular Weight: 390.25834
• Mol file: 1193779-50-8.mol

Synonyms:5-Chloro Bupropion FuMarate;1-(3,5-Dichlorophenyl)-2-[(1,1-diMethylethyl)aMino]-1-propanone (2E)-2-Butenedioate

Chemical Property of 5-Chloro Bupropion FuMarate

Chemical Property:

• PSA: 103.70000
• LogP: 4.05540

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-Chloro Bupropion FuMarate is used in the preparation of compounds for indirect dopamine agonist pharmacotherapy for treating cocaine, methamphetamine, nicotine, and other drugs of abuse addiction.

Technology Process of 5-Chloro Bupropion FuMarate

There total 1 articles about 5-Chloro Bupropion FuMarate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(tert-butylamino)-3',5'-dichloropropiophenone (1193779-48-4) + (2E)-but-2-enedioic acid (110-17-8,26099-09-2) → 2-(tert-butylamino)-3',5'-dichloropropiophenone fumarate (1193779-50-8)

Guidance literature:

In methanol; for 0.25h;

DOI:10.1021/jm901189z

upstream raw materials:

2-(tert-butylamino)-3',5'-dichloropropiophenone

(2E)-but-2-enedioic acid

Refernces

• 1、 Carroll, F. Ivy,Blough, Bruce E.,Abraham, Philip,Mills, Andrew C.,Holleman, J. Ashley,Wolckenhauer, Scott A.,Decker, Ann M.,Landavazo, Antonio,McElroy, K. Timothy,Navarro, Hernán A.,Gatch, Michael B.,Forster, Michael J.. "Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction". supporting information; experimental part. p. 6768 - 6781. Retrieved 2010/04/06.