(2-Chloro-8-methylquinolin-3-yl)methanol

Base Information

Chemical Name:(2-Chloro-8-methylquinolin-3-yl)methanol
CAS No.:333408-31-4
Molecular Formula:C11H10ClNO
Molecular Weight:207.659
Hs Code.:2933499090
European Community (EC) Number:803-461-3
DSSTox Substance ID:DTXSID40357707
Wikidata:Q82137737
Mol file:333408-31-4.mol

Synonyms:333408-31-4;(2-chloro-8-methylquinolin-3-yl)methanol;(2-chloro-8-methyl-3-quinolinyl)methanol;2-Chloro-8-methylquinoline-3-methanol;Oprea1_026196;Oprea1_380107;SCHEMBL717333;DTXSID40357707;GQLHTRIZUUCKGQ-UHFFFAOYSA-N;MFCD02232325;AKOS000126913;2-Chloro-8-methyl-3-quinolinemethanol;SB70515;BS-37854;(2-chloro-8-methyl-quinolin-3-yl)methanol;2-chloro-(8-methylquinolin-3-yl) methanol;CS-0451193;2-Chloro-8-methylquinoline-3-methanol, AldrichCPR;J-508998

Suppliers and Price of (2-Chloro-8-methylquinolin-3-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-8-methylquinoline-3-methanol
50mg
$ 60.00

Sigma-Aldrich
2-Chloro-8-methylquinoline-3-methanol Aldrich
1g
$ 140.00

ChemBridge Corporation
(2-chloro-8-methyl-3-quinolinyl)methanol 95%
1 g
$ 46.00

American Custom Chemicals Corporation
(2-CHLORO-8-METHYLQUINOLIN-3-YL)METHANOL 95.00%
5MG
$ 496.28

AK Scientific
(2-Chloro-8-methylquinolin-3-yl)methanol
1g
$ 224.00

Total 12 raw suppliers

Chemical Property of (2-Chloro-8-methylquinolin-3-yl)methanol

Chemical Property:

Vapor Pressure:4.36E-06mmHg at 25°C
Boiling Point:368.7°C at 760 mmHg
Flash Point:176.8°C
PSA：33.12000
Density:1.307g/cm³
LogP:2.68890
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:207.0450916
Heavy Atom Count:14
Complexity:200

Purity/Quality:

98%Min ^*data from raw suppliers

2-Chloro-8-methylquinoline-3-methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=CC=C1)C=C(C(=N2)Cl)CO

Technology Process of (2-Chloro-8-methylquinolin-3-yl)methanol

There total 2 articles about (2-Chloro-8-methylquinolin-3-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 73568-26-0
2-chloro-8-methyl-quinoline-3-carbaldehyde

: 333408-31-4
2-chloro-3-(hydroxymethyl)-8-methylquinoline

Guidance literature:: 2-chloro-8-methyl-quinoline-3-carbaldehyde; With sodium tetrahydroborate; In tetrahydrofuran; at 20 ℃; for 2h;

With sodium hydrogencarbonate; In water;

Reference yield:

: 120-66-1
N-(2-methylphenyl)acetamide

: 333408-31-4
2-chloro-3-(hydroxymethyl)-8-methylquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 80 - 90 °C

2: sodium tetrahydroborate; water / 0.02 h / 20 °C

With sodium tetrahydroborate; water;
DOI:10.2478/s11696-010-0058-y

Reference yield: 76.0%

: 333408-31-4
2-chloro-3-(hydroxymethyl)-8-methylquinoline

: 10365-98-7,1107579-37-2
3-methoxyphenylboronic acid

: 1167543-97-6
[2-(3-methoxyphenyl)-8-methylquinolin-3-yl]methanol

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; at 150 ℃; for 1h; microwave irradiation;