6-CHLOROPURINE GLUCOSIDE

Base Information

• Chemical Name: 6-CHLOROPURINE GLUCOSIDE
• CAS No.: 66981-23-5
• Molecular Formula: C₁₁H₁₃ClN₄O₅
• Molecular Weight: 316.701
• Mol file: 66981-23-5.mol

Synonyms:6-CHLOROPURINE GLUCOSIDE;6-CHLOROPURINE-9- -D-GLUCOSIDE (6Cl9G);6-Chloro-9-beta-D-glucopyranosyl-9H-purine

Chemical Property of 6-CHLOROPURINE GLUCOSIDE

Chemical Property:

• PSA: 133.75000
• LogP: -1.54790

Purity/Quality:

97% ^*data from raw suppliers

6-CHLOROPURINE GLUCOSIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 6-Chloropurine-9-β-D-glucoside is a metabolite of 6-Chloropurine (C379850), a compound showing antitumor activity against animal and human neoplasms. Plant cytokinin metabolite.

Technology Process of 6-CHLOROPURINE GLUCOSIDE

There total 2 articles about 6-CHLOROPURINE GLUCOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-chloro-9-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)purine (3624-38-2) → 1-(6-chloro-purin-9-yl)-β-D-1-deoxy-glucopyranose (66981-23-5)

Guidance literature:

With ammonia; In methanol; at 0 ℃; for 3h;

DOI:10.1016/j.carres.2007.08.009

Reference yield:

→ 1-(6-chloro-purin-9-yl)-β-D-1-deoxy-glucopyranose (66981-23-5)

Guidance literature:

8 durch Deacetylierung mit H3C-OH/NH3;

DOI:10.1071/CH9781095

Reference yield:

1-(6-chloro-purin-9-yl)-β-D-1-deoxy-glucopyranose (66981-23-5) + benzaldehyde dimethyl acetal (1125-88-8) → 9-(4',6'-O-benzylidene-β-D-glucopyranosyl)-H-6-chloropurine (1000376-94-2)

Guidance literature:

With camphor-10-sulfonic acid; In acetonitrile; at 20 ℃; for 18h;

DOI:10.1016/j.carres.2007.08.009

upstream raw materials:

6-chloro-9-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)purine

Downstream raw materials:

9-(4',6'-O-benzylidene-β-D-glucopyranosyl)-H-6-chloropurine

Refernces

• 1、 Cowley,Duke,Liepa,et al.. "The structure and synthesis of cytokinin metabolites. I. The 7- and 9-β-D-glucofuranosides and pyranosides of zeatin and 6-benzylaminopurine". . p. 1095 - 1111,1100, 1107. Retrieved 2007/10/09.