5-Pyrimidinecarboxylic acid, 2-amino-4-hydroxy-6-methyl- (6CI,8CI)

Base Information

• Chemical Name: 5-Pyrimidinecarboxylic acid, 2-amino-4-hydroxy-6-methyl- (6CI,8CI)
• CAS No.: 23945-48-4
• Molecular Formula: C6H7N3O3
• Molecular Weight: 169.14
• Hs Code.: 2933599090
• Mol file: 23945-48-4.mol

Synonyms:5-Pyrimidinecarboxylic acid, 2-amino-4-hydroxy-6-methyl- (6CI,8CI)

Chemical Property of 5-Pyrimidinecarboxylic acid, 2-amino-4-hydroxy-6-methyl- (6CI,8CI)

Chemical Property:

• PSA: 110.06000
• LogP: -0.29890

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Pyrimidinecarboxylic acid, 2-amino-4-hydroxy-6-methyl- (6CI,8CI)

There total 4 articles about 5-Pyrimidinecarboxylic acid, 2-amino-4-hydroxy-6-methyl- (6CI,8CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-6-methyl-3H-pyrimidin-4-one (3977-29-5) → 2-amino-4-methyl-6-oxo-1,6-dihydro-pyrimidine-5-carboxylic acid (23945-48-4)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol; aqueous KOH

2: KMnO₄; water; NaOH

With potassium hydroxide; sodium hydroxide; potassium permanganate; ethanol; water;

DOI:10.1111/0002-9092.00141

Reference yield:

2-amino-4-methyl-6-oxo-1,6-dihydro-pyrimidine-5-carbaldehyde (18595-67-0) → 2-amino-4-methyl-6-oxo-1,6-dihydro-pyrimidine-5-carboxylic acid (23945-48-4)

Guidance literature:

With sodium hydroxide; potassium permanganate; water;

DOI:10.1111/0002-9092.00141

Reference yield:

2-amino-6-methyl-5-(2,2,2-trichloro-1-hydroxy-ethyl)-3H-pyrimidin-4-one (99513-12-9) → 2-amino-4-methyl-6-oxo-1,6-dihydro-pyrimidine-5-carboxylic acid (23945-48-4)

Guidance literature:

Multi-step reaction with 2 steps

1: aq.-ethanolic KOH

2: KMnO₄; water; NaOH

With potassium hydroxide; sodium hydroxide; potassium permanganate; water;

DOI:10.1111/0002-9092.00141

upstream raw materials:

2-amino-4-methyl-6-oxo-1,6-dihydro-pyrimidine-5-carbaldehyde

2-amino-6-methyl-5-(2,2,2-trichloro-1-hydroxy-ethyl)-3H-pyrimidin-4-one

2-amino-6-methyl-3H-pyrimidin-4-one