(E)-1-(2-CHLORO-5-THIAZOLYLMETHYL)-3-METHYL-2-NITROGUANIDINE

Base Information

• Chemical Name: (E)-1-(2-CHLORO-5-THIAZOLYLMETHYL)-3-METHYL-2-NITROGUANIDINE
• CAS No.: 205510-53-8
• Molecular Formula: C₆H₈ClN₅O₂S
• Molecular Weight: 249.681
• Mol file: 205510-53-8.mol

Synonyms:1-(2-Chloro-5-thiazolylmethyl)-3-methyl-2-nitroguanidine;Clothianidin;

Chemical Property of (E)-1-(2-CHLORO-5-THIAZOLYLMETHYL)-3-METHYL-2-NITROGUANIDINE

Chemical Property:

• Vapor Pressure: 8.93E-08mmHg at 25°C
• Melting Point: 176.8oC
• Refractive Index: 1.709
• Boiling Point: 435.2 °C at 760 mmHg
• Flash Point: 217 °C
• PSA: 123.37000
• Density: 1.68 g/cm³
• LogP: 1.95820
• Water Solubility.: 327 mg/L at 20℃

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-1-(2-CHLORO-5-THIAZOLYLMETHYL)-3-METHYL-2-NITROGUANIDINE

There total 17 articles about (E)-1-(2-CHLORO-5-THIAZOLYLMETHYL)-3-METHYL-2-NITROGUANIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.8%

C8H11ClN6O2S → clothianidine (210880-92-5,205510-53-8)

Guidance literature:

With hydrogenchloride; dihydrogen peroxide; In water; at 70 ℃; for 4h; Solvent; Reagent/catalyst; Temperature;

Reference yield: 95.6%

O-methyl-N-(2-chloro-5-thiazolylmethyl)-N'-nitroisourea (187149-02-6) → clothianidine (210880-92-5,205510-53-8)

Guidance literature:

With hydrogenchloride; methylamine; In water;

Reference yield: 93.4%

C9H13ClN6O2S → clothianidine (210880-92-5,205510-53-8)

Guidance literature:

With dihydrogen peroxide; potassium hydroxide; In water; at 40 ℃; for 4h; Reagent/catalyst; Temperature;

upstream raw materials:

C₁₀H₁₅ClN₆O₂S

2-methyl-1-nitroisourea

[(2-chloro-5-thiazolyl)methyl]amine

O-methyl-N-(2-chloro-5-thiazolylmethyl)-N'-nitroisourea

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