7-Nonynoic acid

Base Information

• Chemical Name: 7-Nonynoic acid
• CAS No.: 56630-32-1
• Molecular Formula: C9H14O2
• Molecular Weight: 154.209
• Mol file: 56630-32-1.mol

Synonyms:7-Nonynoic acid

Chemical Property of 7-Nonynoic acid

Chemical Property:

• Melting Point: 7.8°C (estimate)
• Refractive Index: 1.4008 (estimate)
• Boiling Point: 308.54°C (rough estimate)
• PSA: 37.30000
• Density: 1.0249 (rough estimate)
• LogP: 2.04480

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-Nonynoic acid

There total 16 articles about 7-Nonynoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

5-Heptinylmalonsaeure (85484-79-3) → non-7-ynoic acid (56630-32-1)

Guidance literature:

In pyridine; for 20h; Heating;

Reference yield:

ethyl non-7-ynoate → non-7-ynoic acid (56630-32-1)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; water; at 0 - 20 ℃;

DOI:10.1002/anie.202105732

Reference yield:

hept-5-yn-1-ol (58944-42-6) → non-7-ynoic acid (56630-32-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 95 percent / pyridine / CH₂Cl₂ / 24 h / Ambient temperature

2: 1) NaH / 1) benzene, HMPT, 2,5 h, 60 deg C, 2) benzene, 14 h, reflux

3: 61 percent / 2 M KOH / methanol; H₂O / 48 h / Heating

4: 93 percent / pyridine / 20 h / Heating

With pyridine; potassium hydroxide; sodium hydride; In pyridine; methanol; dichloromethane; water;

upstream raw materials:

1-iodo-6-octyne

potassium cyanide

Nonin-(7)-saeuremethylester

5-Heptinylmalonsaeure

Downstream raw materials:

7-hexadecenoic acid-16-hydroxy-O-lactone

Nonin-(7)-saeuremethylester

Refernces

• 1、 Robinson, John A.,Flohr, Helmut,Kempe, Uwe Max,Pannhorst, Wolfgang,Retey, Janos. "Synthesis, Characterization, and Stereochemistry of Bridged Intramolecularly Alkylated Cobaloximes; Monomeric and Dimeric Complexes of Different Configuration". . p. 181 - 203. Retrieved 2007/10/02.