11-ALPHA-HYDROXY-4-PREGNENE-3,20-DIONE 11-HEMISUCCINATE

Base Information

• Chemical Name: 11-ALPHA-HYDROXY-4-PREGNENE-3,20-DIONE 11-HEMISUCCINATE
• CAS No.: 41238-98-6
• Molecular Formula: C₂₅H₃₄O₆
• Molecular Weight: 430.541
• Mol file: 41238-98-6.mol

Synonyms:4-PREGNEN-11-ALPHA-OL-3,20-DIONE HEMISUCCINATE;4-PREGNEN-11-ALPHA-OL-3,20-DIONE HEMISUCCINATE : BSA;4-PREGNEN-11-ALPHA-OL-3,20-DIONE 11-HEMISUCCINATE;11-ALPHA-HYDROXYPROGESTERONE 11-HEMISUCCINATE;11-ALPHA-HYDROXYPROGESTERONE HEMISUCCINATE;11-ALPHA-HYDROXYPROGESTERONE HEMISUCCINATE : BSA;11-ALPHA-HYDROXY-4-PREGNENE-3,20-DIONE 11-HEMISUCCINATE;11A-hydroxyprogesterone 11-*hemisuccinate

Chemical Property of 11-ALPHA-HYDROXY-4-PREGNENE-3,20-DIONE 11-HEMISUCCINATE

Chemical Property:

• Vapor Pressure: 4.26E-16mmHg at 25°C
• Boiling Point: 603°C at 760 mmHg
• PKA: 4.39±0.17(Predicted)
• Flash Point: 201.7°C
• PSA: 97.74000
• Density: 1.22g/cm³
• LogP: 4.11000

Purity/Quality:

99% ^*data from raw suppliers

11-ALPHA-HYDROXY-4-PREGNENE-3,20-DIONE 11-HEMISUCCINATE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 11-ALPHA-HYDROXY-4-PREGNENE-3,20-DIONE 11-HEMISUCCINATE

There total 2 articles about 11-ALPHA-HYDROXY-4-PREGNENE-3,20-DIONE 11-HEMISUCCINATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 11α-Hydroxy-progesteron-hemisuccinat (41238-98-6,62624-72-0,79465-93-3)

Guidance literature:

11α-Hydroxy-progesteron, Succinanhydrid;

DOI:10.1016/0039-128X(72)90052-9

Reference yield:

→ Progesteron-11α-hemisuccinat (41238-98-6,62624-72-0,79465-93-3)

Guidance literature:

Entspr. Alkohol, Succinanhydrid;

Reference yield:

11α-Hydroxyprogesterone 11-hemisuccinate (41238-98-6) → 11α-Hydroxyprogesteron-11-succinyltyramin (69317-43-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / dicyclohexylcarbodiimide / dimethylformamide / Ambient temperature; overnight

2: 60 percent / 0.13 M NaHCO₃ / dimethylformamide / 4 h / Ambient temperature

With sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide;

DOI:10.1016/0039-128X(85)90038-8

Downstream raw materials:

11α-Hydroxyprogesteron-11-succinyltyramin

Refernces