3-OXO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-8-CARBALDEHYDE

Base Information

• Chemical Name: 3-OXO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-8-CARBALDEHYDE
• CAS No.: 935758-15-9
• Molecular Formula: C₉H₇NO₃
• Molecular Weight: 177.159
• Hs Code.: 2934999090
• Mol file: 935758-15-9.mol

Synonyms:3-OXO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-8-CARBALDEHYDE;3,4-Dihydro-3-oxo-2H-benzo[b][1,4]oxazine-8-carbaldehyde

Chemical Property of 3-OXO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-8-CARBALDEHYDE

Chemical Property:

• PSA: 58.89000
• LogP: 0.91510

Purity/Quality:

97% ^*data from raw suppliers

3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carbaldehyde 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-OXO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-8-CARBALDEHYDE

There total 2 articles about 3-OXO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-8-CARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

ethyl (2-formyl-6-nitrophenoxy)acetate (110683-71-1) → 3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carbaldehyde (935758-15-9) + C9H7NO4 (1233706-52-9) + C9H9NO4 (1233706-54-1)

Guidance literature:

With hydrogenchloride; tin(II) chloride dihdyrate; In tetrahydrofuran; water;

DOI:10.1021/op100103v

Reference yield:

3-nitrosalicylic aldehyde (5274-70-4) → 3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carbaldehyde (935758-15-9) + C9H7NO4 (1233706-52-9) + C9H9NO4 (1233706-54-1)

Guidance literature:

Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / 2-methyltetrahydrofuran / 0.5 h / 80 °C / Large scale reaction

2: hydrogenchloride; tin(II) chloride dihdyrate / tetrahydrofuran; water

With hydrogenchloride; tin(II) chloride dihdyrate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; 2-methyltetrahydrofuran; water;

DOI:10.1021/op100103v

upstream raw materials:

3-nitrosalicylic aldehyde

ethyl (2-formyl-6-nitrophenoxy)acetate