2-BENZYL-3-HYDRAZINOQUINOXALINE

Base Information

• Chemical Name: 2-BENZYL-3-HYDRAZINOQUINOXALINE
• CAS No.: 223929-23-5
• Molecular Formula: C15H14N4
• Molecular Weight: 250.303
• Hs Code.: 2933990090
• Mol file: 223929-23-5.mol

Synonyms:2-BENZYL-3-HYDRAZINOQUINOXALINE

Chemical Property of 2-BENZYL-3-HYDRAZINOQUINOXALINE

Chemical Property:

• Melting Point: 153-155°
• Boiling Point: 462.1±38.0 °C(Predicted)
• PKA: 1.30±0.40(Predicted)
• PSA: 67.06000
• Density: 1.25±0.1 g/cm3(Predicted)
• LogP: 2.62840

Purity/Quality:

97% ^*data from raw suppliers

2-Benzyl-3-hydrazinoquinoxaline >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BENZYL-3-HYDRAZINOQUINOXALINE

There total 5 articles about 2-BENZYL-3-HYDRAZINOQUINOXALINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-benzyl-3-chloroquinoxaline (49568-78-7) → (3-benzyl-quinoxalin-2-yl)-hydrazine (223929-23-5)

Guidance literature:

With hydrazine; In isopropyl alcohol; for 0.25h; microwave irradiation;

DOI:10.1016/j.bmcl.2005.11.088

Reference yield:

3-benzylquinoxalin-2-one (24949-43-7) → (3-benzyl-quinoxalin-2-yl)-hydrazine (223929-23-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 92.27 percent / phosphoryl chloride / 2 h / Heating

2: 92 percent / NH₂NH₂ / propan-2-ol / 0.25 h / microwave irradiation

With hydrazine; trichlorophosphate; In isopropyl alcohol;

DOI:10.1016/j.bmcl.2005.11.088

Reference yield:

1,2-diamino-benzene (95-54-5) → (3-benzyl-quinoxalin-2-yl)-hydrazine (223929-23-5)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanol / Heating

2: trichlorophosphate

3: hydrazine hydrate / ethanol

With hydrazine hydrate; trichlorophosphate; In ethanol;

DOI:10.1016/j.ejmech.2015.02.020

upstream raw materials:

2-benzyl-3-chloroquinoxaline

3-benzylquinoxalin-2-one

4-benzylidene-2-methyl-2-oxazolin-5-one

1,2-diamino-benzene

Downstream raw materials:

2-{(E)-[(3-benzylquinoxalin-2-yl)hydrazono]methyl}benzoic acid

2-(3-benzylquinoxalin-2-yl)phthalazin-1(2H)-one

3-benzyl-2-(2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)quinoxaline

3-benzyl-2-(2-((3-methylthiophen-2-yl)methylene)hydrazinyl)quinoxaline