2-(4'-Trifluoromethyl[1,1'-biphenyl]-3-yl)ethan-1-one

Base Information

Chemical Name:2-(4'-Trifluoromethyl[1,1'-biphenyl]-3-yl)ethan-1-one
CAS No.:638214-18-3
Molecular Formula:C₁₅H₁₁F₃O
Molecular Weight:264.247
Hs Code.:2914790090
Mol file:638214-18-3.mol

Synonyms:2-(4'-Trifluoromethyl[1,1'-biphenyl]-3-yl)ethan-1-one;3-Acetyl-4'-(trifluoromethyl)biphenyl;1-[4'-(Trifluoromethyl)biphenyl-3-yl]ethan-1-one, 3'-[4-(Trifluoromethyl)phenyl]acetophenone

Suppliers and Price of 2-(4'-Trifluoromethyl[1,1'-biphenyl]-3-yl)ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
3-Acetyl-4'-(trifluoromethyl)biphenyl
1 g
$ 144.00

Crysdot
1-(4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)ethanone 97%
5g
$ 757.00

Apolloscientific
3-Acetyl-4'-(trifluoromethyl)biphenyl
1g
$ 131.00

American Custom Chemicals Corporation
3-ACETYL-4'-(TRIFLUOROMETHYL)BIPHENYL 95.00%
1G
$ 809.66

Total 2 raw suppliers

Chemical Property of 2-(4'-Trifluoromethyl[1,1'-biphenyl]-3-yl)ethan-1-one

Chemical Property:

PSA：17.07000
LogP:4.57500

Purity/Quality:

95% ^*data from raw suppliers

3-Acetyl-4'-(trifluoromethyl)biphenyl ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(4'-Trifluoromethyl[1,1'-biphenyl]-3-yl)ethan-1-one

There total 1 articles about 2-(4'-Trifluoromethyl[1,1'-biphenyl]-3-yl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 128796-39-4
4-trifluoromethylphenylboronic acid

: 2142-63-4
1-(3-Bromophenyl)ethanone

: 638214-18-3
1-[4'-(trifluoromethyl)-3-biphenylyl]ethanone

Guidance literature:: With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; at 80 ℃; for 5h; Sealed tube; Inert atmosphere;

Reference yield:

: 638214-18-3
1-[4'-(trifluoromethyl)-3-biphenylyl]ethanone

: 638215-27-7
{[2-methyl-4-({1-[4'-(trifluoromethyl)-3-biphenylyl] ethyl}thio)phenyl]oxy}acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium tetrahydroborate / ethanol; water / 1.5 h / 20 °C

2.1: acetic acid; zinc / ethyl acetate / 2 h

2.2: 6 h / 20 - 80 °C

3.1: sodium hydroxide; Dowex 50Wx₂ / 1,4-dioxane; water / 1 h / Heating / reflux

With sodium hydroxide; sodium tetrahydroborate; Dowex 50Wx₂; acetic acid; zinc; In 1,4-dioxane; ethanol; water; ethyl acetate;

Reference yield:

: 638214-18-3
1-[4'-(trifluoromethyl)-3-biphenylyl]ethanone

: 638214-20-7
ethyl {[2-methyl-4-({1-[4'-(trifluoromethyl)-3-biphenylyl]ethyl}thio)phenyl]oxy}acetate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium tetrahydroborate / ethanol; water / 1.5 h / 20 °C

2.1: acetic acid; zinc / ethyl acetate / 2 h

2.2: 6 h / 20 - 80 °C

With sodium tetrahydroborate; acetic acid; zinc; In ethanol; water; ethyl acetate;