1,1-dimethyl-5-nitro-3-(2-pyridon-1-yl)indan-2-ol

Base Information

Chemical Name:1,1-dimethyl-5-nitro-3-(2-pyridon-1-yl)indan-2-ol
CAS No.:131406-69-4
Molecular Formula:C₁₆H₁₆N₂O₄
Molecular Weight:300.314
Hs Code.:
Mol file:131406-69-4.mol

Synonyms:1,1-dimethyl-5-nitro-3-(2-pyridon-1-yl)indan-2-ol

Suppliers and Price of 1,1-dimethyl-5-nitro-3-(2-pyridon-1-yl)indan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,1-dimethyl-5-nitro-3-(2-pyridon-1-yl)indan-2-ol

Chemical Property:

Vapor Pressure:5.59E-12mmHg at 25°C
Boiling Point:528°C at 760 mmHg
Flash Point:273.2°C
PSA：88.05000
Density:1.364g/cm³
LogP:2.52120

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,1-dimethyl-5-nitro-3-(2-pyridon-1-yl)indan-2-ol

There total 5 articles about 1,1-dimethyl-5-nitro-3-(2-pyridon-1-yl)indan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 124369-50-2
1,1-Dimethyl-2,3-epoxy-5-nitro-indane

: 124369-35-3
trans-1,1-dimethyl-5-nitroindan-2,3-diol

: 131406-69-4
trans-1,1-dimethyl-5-nitro-3-(2-pyridon-1-yl)indan-2-ol

Guidance literature:: With 2-Pyridone; potassium tert-butylate; In dimethyl sulfoxide; for 72h; Ambient temperature;
DOI:10.1021/jm00107a008

Reference yield: 28.0%

: 142-08-5,1199357-22-6
2-Pyridone

: 124369-50-2
1,1-Dimethyl-2,3-epoxy-5-nitro-indane

: 124369-35-3
trans-1,1-dimethyl-5-nitroindan-2,3-diol

: 131406-69-4
trans-1,1-dimethyl-5-nitro-3-(2-pyridon-1-yl)indan-2-ol

Guidance literature:: With potassium tert-butylate; In dimethyl sulfoxide; for 72h; Ambient temperature;
DOI:10.1021/jm00107a008

Reference yield:

: 67159-79-9
3,3-dimethyl-6-nitro-indan-1-one

: 131406-69-4
trans-1,1-dimethyl-5-nitro-3-(2-pyridon-1-yl)indan-2-ol

Guidance literature:: Multi-step reaction with 4 steps

1: KBH₄ / methanol / 1 h / Ambient temperature

2: p-toluenesulfonic acid / toluene / 16 h / Heating

3: m-chloroperbenzoic acid (m-CPBA) / CH₂Cl₂ / 48 h

4: 42 percent / KO-t-Bu / dimethylsulfoxide / 72 h / Ambient temperature

With potassium borohydride; potassium tert-butylate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane; dimethyl sulfoxide; toluene;
DOI:10.1021/jm00107a008