7-Chloronaphthalene-2-sulfonic acid

Base Information

• Chemical Name: 7-Chloronaphthalene-2-sulfonic acid
• CAS No.: 102878-15-9
• Molecular Formula: C10H7ClO3S
• Molecular Weight: 242.67878
• DSSTox Substance ID: DTXSID20601679
• Wikidata: Q82498466
• Mol file: 102878-15-9.mol

Synonyms:7-Chloronaphthalene-2-sulfonic acid;102878-15-9;SCHEMBL3885658;DTXSID20601679;DLFQBQBIFQCKSO-UHFFFAOYSA-N;DB-083917

Chemical Property of 7-Chloronaphthalene-2-sulfonic acid

Chemical Property:

• PKA: 0.09±0.40(Predicted)
• PSA: 62.75000
• Density: 1.533±0.06 g/cm3(Predicted)
• LogP: 3.82070
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 241.9804429
• Heavy Atom Count: 15
• Complexity: 322

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC2=C1C=CC(=C2)Cl)S(=O)(=O)O

Technology Process of 7-Chloronaphthalene-2-sulfonic acid

There total 3 articles about 7-Chloronaphthalene-2-sulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

7-aminonaphthalene-2-sulfonic acid,sodium salt → 7-chloro-naphthalene-2-sulfonic acid (102878-15-9)

Guidance literature:

7-aminonaphthalene-2-sulfonic acid,sodium salt; With hydrogenchloride; sodium nitrite; In water; at 0 - 20 ℃; for 0.5h; Inert atmosphere;

With copper(l) chloride; In water; at 0 - 20 ℃; for 2.5h;

Reference yield:

7-amino-8-chloro-naphthalene-2-sulfonic acid (859071-31-1) → 7-chloro-naphthalene-2-sulfonic acid (102878-15-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium amalgam

2: durch Austausch der Aminogruppe gegen Chlor

With sodium amalgam;

Reference yield:

7-aminonaphthalene-2-sulfonic acid (494-44-0) → 7-chloro-naphthalene-2-sulfonic acid (102878-15-9)

Guidance literature:

durch Austausch der Aminogruppe gegen Chlor;

upstream raw materials:

7-aminonaphthalene-2-sulfonic acid

7-amino-8-chloro-naphthalene-2-sulfonic acid