4-[(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoic acid

Base Information

Chemical Name:4-[(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoic acid
CAS No.:309923-57-7
Molecular Formula:C16H13NO5
Molecular Weight:299.28
Hs Code.:2932999099
DSSTox Substance ID:DTXSID40387105
ChEMBL ID:CHEMBL1374018
Mol file:309923-57-7.mol

Synonyms:309923-57-7;4-[(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoic acid;4-(2,3-dihydro-1,4-benzodioxine-3-carbonylamino)benzoic acid;4-(2,3-Dihydrobenzo[b][1,4]dioxine-2-carboxamido)benzoic acid;4-[(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzenecarboxylic acid;Benzoic acid, 4-[[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]amino]-;4-((2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)amino)benzenecarboxylic acid;CBMicro_041651;Oprea1_215798;Oprea1_524177;MLS000713570;CHEMBL1374018;DTXSID40387105;HMS2660I11;4-[(2,3-Dihydro-benzo[1,4]dioxine-2-carbonyl)-amino]-benzoic acid;MFCD02048701;STK386502;AKOS000151908;AKOS016148756;SMR000273051;BIM-0041605.P001;CS-0313589;FT-0702935;2X-0808;4-(1,4-benzodioxan-2-ylcarbonylamino)benzoic acid;4-(2,3-dihydro-1,4-benzodioxine-2-amido)benzoic acid;4-(2,3-Dihydrobenzo[b][1,4]dioxine-2-carboxamido)benzoicacid;4-[(2,3-Dihydro-1,4-benzodioxine-2-carbonyl)amino]benzoic acid;4-[(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzenecarboxylic acid, AldrichCPR

Suppliers and Price of 4-[(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemBridge Corporation
4-[(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoicacid 95%
250 mg
$ 64.00

American Custom Chemicals Corporation
4-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLCARBONYL)AMINO]BENZOIC ACID 95.00%
5MG
$ 502.14

Total 2 raw suppliers

Chemical Property of 4-[(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoic acid

Chemical Property:

Vapor Pressure:3.26E-14mmHg at 25°C
Boiling Point:578.3°C at 760 mmHg
PKA:4.24±0.10(Predicted)
Flash Point:303.5°C
PSA：84.86000
Density:1.428g/cm³
LogP:2.23630
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:299.07937252
Heavy Atom Count:22
Complexity:419

Purity/Quality:

99% ^*data from raw suppliers

4-[(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoicacid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(OC2=CC=CC=C2O1)C(=O)NC3=CC=C(C=C3)C(=O)O

Technology Process of 4-[(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoic acid

There total 2 articles about 4-[(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 3663-81-8
1,4-benzodioxan-2-carbonyl chloride

: 150-13-0,159246-81-8,8014-65-1
4-amino-benzoic acid

: 309923-57-7
4-(1,4-b0enzodioxan-2-ylcarbonylamino)benzoic acid

Guidance literature:: With pyridine; In 1,4-dioxane; at 70 ℃;
DOI:10.1134/S1070428012070147

Reference yield:

: 3663-80-7,34385-93-8,70918-53-5,70918-54-6
1,4-benzodioxane-2-carboxylic acid

: 309923-57-7
4-(1,4-b0enzodioxan-2-ylcarbonylamino)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride

2: pyridine / 1,4-dioxane / 70 °C

With pyridine; thionyl chloride; In 1,4-dioxane;
DOI:10.1134/S1070428012070147