2,3,5-Trifluoro-6-(hex-1-yn-1-yl)-4-(trifluoromethyl)aniline

Base Information

Chemical Name:2,3,5-Trifluoro-6-(hex-1-yn-1-yl)-4-(trifluoromethyl)aniline
CAS No.:1363411-71-5
Molecular Formula:C₁₃H₁₁F₆N
Molecular Weight:295.227
Hs Code.:
Mol file:1363411-71-5.mol

Synonyms:2,3,5-Trifluoro-6-(hex-1-yn-1-yl)-4-(trifluoromethyl)aniline

Suppliers and Price of 2,3,5-Trifluoro-6-(hex-1-yn-1-yl)-4-(trifluoromethyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2,3,5-Trifluoro-6-(hex-1-yn-1-yl)-4-(trifluoromethyl)aniline

Chemical Property:

Purity/Quality:: ≥99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,3,5-Trifluoro-6-(hex-1-yn-1-yl)-4-(trifluoromethyl)aniline

There total 2 articles about 2,3,5-Trifluoro-6-(hex-1-yn-1-yl)-4-(trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1363411-68-0
2-iodo-3,5,6-trifluoro-4-(trifluoromethyl)aniline

: 693-02-7
hex-1-yne

: 1363411-71-5
2,3,5-trifluoro-6-(hex-1-yn-1-yl)-4-(trifluoromethyl)aniline

Guidance literature:: With copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; sodium acetate; triethylamine; at 70 ℃; for 3h; Inert atmosphere;
DOI:10.1016/j.jfluchem.2011.09.008

Reference yield:

: 123950-43-6
2,3,5-trifluoro-4-(trifluoromethyl)aniline

: 1363411-71-5
2,3,5-trifluoro-6-(hex-1-yn-1-yl)-4-(trifluoromethyl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: iodine; iodic acid / 1,4-dioxane; water / 4 h / Reflux

2: copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; sodium acetate; triethylamine / 3 h / 70 °C / Inert atmosphere

With copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; iodine; sodium acetate; iodic acid; triethylamine; In 1,4-dioxane; water; 2: Sonogashira coupling;
DOI:10.1016/j.jfluchem.2011.09.008