(1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL

Base Information

Chemical Name:(1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL
CAS No.:327611-65-4
Molecular Formula:C11H21NO
Molecular Weight:183.294
Hs Code.:
Mol file:327611-65-4.mol

Synonyms:(1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL

Suppliers and Price of (1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO(3.1.1)HEPT-3-YL)-METHANOL 95.00%
5MG
$ 498.94

Total 1 raw suppliers

Chemical Property of (1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL

Chemical Property:

Vapor Pressure:0.00215mmHg at 25°C
Boiling Point:257.5°C at 760 mmHg
Flash Point:109.6°C
PSA：46.25000
Density:0.973g/cm³
LogP:2.07860

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

(1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO(3.1.1)HEPT-3-YL)-METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL

There total 5 articles about (1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 327611-64-3
ethyl (1S,2S,3R,5S)-2-amino-2,6,6-trimethylbicyclo[3.1.1]heptane-3-carboxylate

: 327611-65-4
(1S,2S,3R,5S)-2-amino-3-hydroxymethyl-2,6,6-trimethylbicyclo[3.1.1]heptane

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 2h; Reflux;
DOI:10.1007/s11172-008-0017-8

Reference yield:

: 35182-62-8,328010-05-5
(1S,2S,5R,7S)-2,8,8-trimethyl-3-azatricyclo[5.1.1.0^2,5]nonan-4-one

: 327611-65-4
(1S,2S,3R,5S)-2-amino-3-hydroxymethyl-2,6,6-trimethylbicyclo[3.1.1]heptane

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / 10 percent HCl / 12 h / Heating

2: 85 percent / LiAlH₄ / tetrahydrofuran / 2 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran;
DOI:10.1016/S0957-4166(00)00435-3

Reference yield:

: 7785-70-8,25766-18-1
(+)-α-pinene

: 327611-65-4
(1S,2S,3R,5S)-2-amino-3-hydroxymethyl-2,6,6-trimethylbicyclo[3.1.1]heptane

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / diethyl ether / 1 h

2: 60 percent / 10 percent HCl / 12 h / Heating

3: 85 percent / LiAlH₄ / tetrahydrofuran / 2 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether;
DOI:10.1016/S0957-4166(00)00435-3