2-Pyrrolidinecarbonyl chloride, 1-methyl-5-oxo- (9CI)

Base Information

• Chemical Name: 2-Pyrrolidinecarbonyl chloride, 1-methyl-5-oxo- (9CI)
• CAS No.: 42435-90-5
• Molecular Formula: C6H8ClNO2
• Molecular Weight: 161.58622
• Hs Code.: 2933790090
• Mol file: 42435-90-5.mol

Synonyms:2-Pyrrolidinecarbonyl chloride, 1-methyl-5-oxo- (9CI)

Chemical Property of 2-Pyrrolidinecarbonyl chloride, 1-methyl-5-oxo- (9CI)

Chemical Property:

• PSA: 37.38000
• LogP: 0.31050

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Pyrrolidinecarbonyl chloride, 1-methyl-5-oxo- (9CI)

There total 3 articles about 2-Pyrrolidinecarbonyl chloride, 1-methyl-5-oxo- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S)-1-methyl-5-oxopyrrolidine-2-carboxylic acid (52574-06-8,952345-00-5) → 1-methyl-5-oxoprolyl chloride (42435-90-5)

Guidance literature:

With 1-chloro-1-(dimethylamino)-2-methyl-1-propene; In dichloromethane; at 20 ℃; for 0.333333h;

Reference yield:

1-methyl-5-oxopyrrolidine-2-carboxylic acid (72442-37-6,952345-00-5) → 1-methyl-5-oxoprolyl chloride (42435-90-5)

Guidance literature:

With thionyl chloride;

DOI:10.1002/hlca.19550380137

Reference yield:

→ 1-methyl-5-oxoprolyl chloride (42435-90-5)

Guidance literature:

6, SOCl2;

upstream raw materials:

1-methyl-5-oxopyrrolidine-2-carboxylic acid

(2S)-1-methyl-5-oxopyrrolidine-2-carboxylic acid

Refernces

• 1、 -. "SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF". Page/Page column 81. . Retrieved 2019/06/05.