Methyl 3-[(2-methoxyethyl)amino]propanoate

Base Information

• Chemical Name: Methyl 3-[(2-methoxyethyl)amino]propanoate
• CAS No.: 55694-53-6
• Molecular Formula: C₇H₁₅NO₃
• Molecular Weight: 161.201
• Hs Code.: 2922509090
• Mol file: 55694-53-6.mol

Synonyms:Methyl 3-[(2-methoxyethyl)amino]propanoate

Chemical Property of Methyl 3-[(2-methoxyethyl)amino]propanoate

Chemical Property:

• PSA: 47.56000
• LogP: 0.17640

Purity/Quality:

98%min ^*data from raw suppliers

Methyl3-[(2-methoxyethyl)amino]propanoate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 3-[(2-methoxyethyl)amino]propanoate

There total 1 articles about Methyl 3-[(2-methoxyethyl)amino]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ methyl 3-(2-methoxyethylamino)propanoate (55694-53-6)

Guidance literature:

at 20 ℃;

Reference yield:

methyl 3-(2-methoxyethylamino)propanoate (55694-53-6) → C18H20N4O4 (1429324-67-3)

Guidance literature:

Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / acetonitrile / Reflux

2: potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; XPhos / 1,4-dioxane; water / 70 °C / Inert atmosphere

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; N-ethyl-N,N-diisopropylamine; XPhos; In 1,4-dioxane; water; acetonitrile; 2: |Suzuki Coupling;

Reference yield:

methyl 3-(2-methoxyethylamino)propanoate (55694-53-6) → C19H22N4O4 (1429324-68-4)

Guidance literature:

Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / acetonitrile / Reflux

2: potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; XPhos / 1,4-dioxane; water / 70 °C / Inert atmosphere

3: sulfuric acid / methanol / 4 h / Reflux

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sulfuric acid; N-ethyl-N,N-diisopropylamine; XPhos; In 1,4-dioxane; methanol; water; acetonitrile; 2: |Suzuki Coupling;

Downstream raw materials:

C₁₈H₂₀N₄O₄

C₁₉H₂₂N₄O₄

Refernces