4-bromo-2,5-dimethylbenzenesulfonyl chloride(SALTDATA: FREE)

Base Information

• Chemical Name: 4-bromo-2,5-dimethylbenzenesulfonyl chloride(SALTDATA: FREE)
• CAS No.: 14207-30-8
• Molecular Formula: C8H8BrClO2S
• Molecular Weight: 283.573
• Hs Code.: 2904909090
• Mol file: 14207-30-8.mol

Synonyms:4-bromo-2,5-dimethylbenzenesulfonyl chloride(SALTDATA: FREE);4-Bromo-2,5-dimethyl-benzenesulfonyl chloride

Chemical Property of 4-bromo-2,5-dimethylbenzenesulfonyl chloride(SALTDATA: FREE)

Chemical Property:

• Melting Point: 55 °C
• Boiling Point: 140 °C(Press: 2 Torr)
• PSA: 42.52000
• Density: 1.622±0.06 g/cm3(Predicted)
• LogP: 4.07420

Purity/Quality:

99% ^*data from raw suppliers

4-Bromo-2,5-dimethyl-benzenesulfonylchloride 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-bromo-2,5-dimethylbenzenesulfonyl chloride(SALTDATA: FREE)

There total 1 articles about 4-bromo-2,5-dimethylbenzenesulfonyl chloride(SALTDATA: FREE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-bromo-m-xylene (553-94-6) → 4-bromo-2,5-dimethylbenzenesulfonyl chloride (14207-30-8)

Guidance literature:

With chlorosulfonic acid; In chloroform; at 0 - 20 ℃; for 4.5h;

DOI:10.1002/chem.201604966

Reference yield: 99.0%

4-bromo-2,5-dimethylbenzenesulfonyl chloride (14207-30-8) + 2-Methylpiperidin (109-05-7,3000-79-1) → 1-(4-bromo-2,5-dimethylphenylsulfonyl)-2-methylpiperidine (898655-70-4)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1016/j.ejmech.2013.01.047

Reference yield:

4-bromo-2,5-dimethylbenzenesulfonyl chloride (14207-30-8) → 4-bromo-2,5-dimethyl-benzenesulfonic acid amide (14207-31-9)

Guidance literature:

With ammonium hydroxide; In tetrahydrofuran; water; for 0.166667h;

upstream raw materials:

4-bromo-m-xylene

Downstream raw materials:

4-bromo-2,5-dimethylbenzenethiol

4-<4'-Brom-2'.5'-dimethyl-phenyl>-4-thia-3-methyl-butan-2-on

4-bromo-2,5-dimethyl-benzenesulfonic acid amide

C₁₃H₁₉BrN₂O₂S

Refernces

• 1、 Berg, Stefan,Bergh, Margareta,Hellberg, Sven,Hoegdin, Katharina,Lo-Alfredsson, Yvonne,Soederman, Peter,Von Berg, Stefan,Weigelt, Tatjana,Ormoe, Mats,Xue, Yafeng,Tucker, Julie,Neelissen, Jan,Jerning, Eva,Nilsson, Yvonne,Bhat, Ratan. "Discovery of novel potent and highly selective glycogen synthase kinase-3β (GSK3β) inhibitors for Alzheimers Disease: Design, synthesis, and characterization of pyrazines". . p. 9107 - 9119,13. Retrieved 2020/10/15.