2-Chloro-6-methylquinoline-3-methanol

Base Information

Chemical Name:2-Chloro-6-methylquinoline-3-methanol
CAS No.:123637-97-8
Molecular Formula:C11H10ClNO
Molecular Weight:207.659
Hs Code.:2933499090
European Community (EC) Number:802-737-0
DSSTox Substance ID:DTXSID00357708
Wikidata:Q82137739
Mol file:123637-97-8.mol

Synonyms:2-Chloro-6-methylquinoline-3-methanol;123637-97-8;(2-chloro-6-methylquinolin-3-yl)methanol;2-chloro-6-methylquinolin-3-ylmethanol;Oprea1_259430;Oprea1_586621;SCHEMBL14617053;DTXSID00357708;HMS1672I03;YEA63797;MFCD02232327;AKOS000589295;2-Chloro-6-methyl-3-quinolinemethanol;SB70593;CS-0215432;EN300-246866;2-Chloro-6-methylquinoline-3-methanol, AldrichCPR

Suppliers and Price of 2-Chloro-6-methylquinoline-3-methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-6-methylquinoline-3-methanol
500mg
$ 330.00

SynQuest Laboratories
2-Chloro-6-methylquinoline-3-methanol
5 g
$ 928.00

SynQuest Laboratories
2-Chloro-6-methylquinoline-3-methanol
1 g
$ 328.00

Sigma-Aldrich
2-Chloro-6-methylquinoline-3-methanol Aldrich
1g
$ 223.00

Apolloscientific
2-Chloro-6-methylquinoline-3-methanol
1g
$ 298.00

Apolloscientific
2-Chloro-6-methylquinoline-3-methanol
5g
$ 841.00

American Custom Chemicals Corporation
2-CHLORO-6-METHYLQUINOLINE-3-METHANOL 95.00%
5MG
$ 503.01

AK Scientific
2-Chloro-6-methylquinoline-3-methanol
1g
$ 328.00

Total 4 raw suppliers

Chemical Property of 2-Chloro-6-methylquinoline-3-methanol

Chemical Property:

Vapor Pressure:4.36E-06mmHg at 25°C
Boiling Point:368.7°C at 760 mmHg
Flash Point:176.8°C
PSA：33.12000
Density:1.307g/cm³
LogP:2.68890
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:207.0450916
Heavy Atom Count:14
Complexity:200

Purity/Quality:

98%+ ^*data from raw suppliers

2-Chloro-6-methylquinoline-3-methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=CC(=C(N=C2C=C1)Cl)CO

Technology Process of 2-Chloro-6-methylquinoline-3-methanol

There total 4 articles about 2-Chloro-6-methylquinoline-3-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.4%

: 73568-27-1
2-chloro-6-methylquinoline-3-carbaldehyde

: 123637-97-8
3-(hydroxymethyl)-2-chloro-6-methylquinoline

Guidance literature:: With sodium tetrahydroborate; In methanol; at 20 ℃; for 0.166667h;
DOI:10.1134/S1070428009030142

Reference yield:

: 103-89-9
4-Methylacetanilide

: 123637-97-8
3-(hydroxymethyl)-2-chloro-6-methylquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate / 80 - 90 °C

2: methanol; sodium tetrahydroborate / 0.5 h / 20 °C

With methanol; sodium tetrahydroborate; trichlorophosphate;
DOI:10.1007/s12039-011-0127-y

Reference yield:

: C₁₂H₁₁ClN₂O

: 123637-97-8
3-(hydroxymethyl)-2-chloro-6-methylquinoline

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / Cooling

1.2: Reflux

2.1: sodium tetrahydroborate / methanol / 20 °C

With sodium tetrahydroborate; trichlorophosphate; In methanol; 1.1: |Vilsmeier-Haack Formylation / 1.2: |Vilsmeier-Haack Formylation;
DOI:10.1016/j.ejmech.2017.01.043