(1,1-Dioxothiolan-3-yl)methanol

Base Information

Chemical Name:(1,1-Dioxothiolan-3-yl)methanol
CAS No.:17236-20-3
Molecular Formula:C6H7N
Molecular Weight:150.199
Hs Code.:
European Community (EC) Number:818-126-7

Synonyms:17236-20-3;3-Methyl pyrlidine;(1,1-dioxothiolan-3-yl)methanol;3-(hydroxymethyl)tetrahydrothiophene 1,1-dioxide;(1,1-dioxidotetrahydro-3-thienyl)methanol;MFCD03038032;3-Methylpyrlidine;(1,1-Dioxo-tetrahydrothiophen-3-yl)methanol;3-Thiophenemethanol, tetrahydro-, 1,1-dioxide;SCHEMBL283856;PJKMZHYNDJRIHG-UHFFFAOYSA-N;STL454396;AKOS002275036;AKOS016047287;AT13046;BS-37386;SY148465;Tetrahydrothiophene-3-methanol 1,1-dioxide;CS-0448364;(1,1-dioxidotetrahydrothiophen-3-yl)methanol;3-(hydroxymethyl)-1lambda-thiolane-1,1-dione;EN300-127602;3-(hydroxymethyl)-1lambda6-thiolane-1,1-dione;Z57161971;(1,1-Dioxidotetrahydro-3-thienyl)methanol, AldrichCPR;F1294-0070;(1,1-dioxo-tetrahydro-1lambda*6*-thiophen-3-yl)-methanol

Suppliers and Price of (1,1-Dioxothiolan-3-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of (1,1-Dioxothiolan-3-yl)methanol

Chemical Property:

XLogP3:-0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:150.03506535
Heavy Atom Count:9
Complexity:177

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CS(=O)(=O)CC1CO

Technology Process of (1,1-Dioxothiolan-3-yl)methanol

There total 5 articles about (1,1-Dioxothiolan-3-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.5%

: 4785-67-5
1,1-dioxo-tetrahydro-1λ⁶-thiophene-3-carboxylic acid

: 17236-20-3
3-(hydroxymethyl)tetrahydrothiophene 1,1-dioxide

Guidance literature:: 1,1-dioxo-tetrahydro-1λ⁶-thiophene-3-carboxylic acid; With 4-methyl-morpholine; chloroformic acid ethyl ester; In tetrahydrofuran; at -10 ℃; for 0.266667h;

With sodium tetrahydroborate; water; In tetrahydrofuran; at 5 - 20 ℃; for 2h;

Reference yield: 36.0%

: 720719-20-0
3-hydroxymethyltetrahydrothiophene

: 3-hydroxymethyltetrahydrothiophene 1-oxide

: 17236-20-3
3-(hydroxymethyl)tetrahydrothiophene 1,1-dioxide

Guidance literature:: With sodium periodate; In methanol; water; at 0 - 20 ℃;
DOI:10.1021/jo0497306

Reference yield:

: 55881-94-2
3-methylene-1,4-dihydroxybutane

: 17236-20-3
3-(hydroxymethyl)tetrahydrothiophene 1,1-dioxide

Guidance literature:: Multi-step reaction with 4 steps

1.1: 86 percent / Na₂S*2H₂O / aq. ethanol

2.1: BH₃*Me₂S / 1 h / 20 °C

2.2: 61 percent / aq. NaOH; aq. H₂O₂ / 2 h / 20 °C

3.1: 36 percent / NaIO₄ / methanol; H₂O / 0 - 20 °C

With sodium sulfide; sodium periodate; dimethylsulfide borane complex; In methanol; ethanol; water;
DOI:10.1021/jo0497306