[2R,(+)]-Tetrahydro-4-methylene-5-oxo-2-undecyl-3β-furancarboxylic acid

Base Information

Chemical Name:[2R,(+)]-Tetrahydro-4-methylene-5-oxo-2-undecyl-3β-furancarboxylic acid
CAS No.:70630-67-0
Molecular Formula:C17H28O4
Molecular Weight:296.40182
Hs Code.:
Mol file:70630-67-0.mol

Synonyms:(+)-Nephrosterinic acid;[2R,(+)]-Tetrahydro-4-methylene-5-oxo-2-undecyl-3β-furancarboxylic acid

Suppliers and Price of [2R,(+)]-Tetrahydro-4-methylene-5-oxo-2-undecyl-3β-furancarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of [2R,(+)]-Tetrahydro-4-methylene-5-oxo-2-undecyl-3β-furancarboxylic acid

Chemical Property:

PSA：63.60000
LogP:4.08970

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [2R,(+)]-Tetrahydro-4-methylene-5-oxo-2-undecyl-3β-furancarboxylic acid

There total 12 articles about [2R,(+)]-Tetrahydro-4-methylene-5-oxo-2-undecyl-3β-furancarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 376587-45-0
nephrosterinic acid methyl ester

: 570-13-8,58785-73-2,58785-74-3,60427-66-9,60464-10-0,70630-67-0
(-)-nephrosterinic acid

Guidance literature:: With hydrogenchloride; In water; butanone; for 2h; Heating;
DOI:10.1016/S0957-4166(01)00345-7

Reference yield:

: 112-54-9
Dodecanal

: 570-13-8,58785-73-2,58785-74-3,60427-66-9,60464-10-0,70630-67-0
(-)-nephrosterinic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: lithium diisopropylamide / tetrahydrofuran / 2 h / -78 - 0 °C

1.2: 63 percent / tetrahydrofuran / 3 h / -78 - 20 °C

2.1: 75 percent / sodium methoxide / tetrahydrofuran; methanol / 48 h / 20 °C

3.1: 77 percent / Pyrolysis

4.1: 79 percent / hydrochloric acid / H₂O; butan-2-one / 2 h / Heating

With hydrogenchloride; sodium methylate; lithium diisopropyl amide; In tetrahydrofuran; methanol; water; butanone; 3.1: retro Diels-Alder reaction;
DOI:10.1016/S0957-4166(01)00345-7

Reference yield:

: 11-carbomethoxy-11-methoxycarbonylmethyl-9,10-dihydro-9,10-ethanoanthracene

: 570-13-8,58785-73-2,58785-74-3,60427-66-9,60464-10-0,70630-67-0
(-)-nephrosterinic acid

Guidance literature:: Multi-step reaction with 8 steps

1.1: 97 percent / potassium hydroxide / H₂O; methanol / 2 h / Heating

2.1: thionyl chloride; dimethylformamide / 2 h / Heating

3.1: 34 percent / triethylamine / benzene / 2 h / Heating

4.1: 95 percent / H₂SO₄ / 168 h / Heating

5.1: lithium diisopropylamide / tetrahydrofuran / 2 h / -78 - 0 °C

5.2: 63 percent / tetrahydrofuran / 3 h / -78 - 20 °C

6.1: 75 percent / sodium methoxide / tetrahydrofuran; methanol / 48 h / 20 °C

7.1: 77 percent / Pyrolysis

8.1: 79 percent / hydrochloric acid / H₂O; butan-2-one / 2 h / Heating

With hydrogenchloride; potassium hydroxide; thionyl chloride; sulfuric acid; sodium methylate; triethylamine; N,N-dimethyl-formamide; lithium diisopropyl amide; In tetrahydrofuran; methanol; water; butanone; benzene; 7.1: retro Diels-Alder reaction;
DOI:10.1016/S0957-4166(01)00345-7