5-((4S)-2-oxohexahydro-1H-thieno[3,4-d]iMidazol-4-yl)pentanehydrazide

Base Information

• Chemical Name: 5-((4S)-2-oxohexahydro-1H-thieno[3,4-d]iMidazol-4-yl)pentanehydrazide
• CAS No.: 1214641-84-5
• Molecular Formula: C10H18N4O2S
• Molecular Weight: 258.34052
• Mol file: 1214641-84-5.mol

Synonyms:1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazide, (4S)-;5-[(4S)-2-Oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanehydrazide

Chemical Property of 5-((4S)-2-oxohexahydro-1H-thieno[3,4-d]iMidazol-4-yl)pentanehydrazide

Chemical Property:

• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

5-((4S)-2-Oxohexahydro-1H-thieno-[3,4-d]imidazol-4-yl)pentanehydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-((4S)-2-oxohexahydro-1H-thieno[3,4-d]iMidazol-4-yl)pentanehydrazide

There total 3 articles about 5-((4S)-2-oxohexahydro-1H-thieno[3,4-d]iMidazol-4-yl)pentanehydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

biotin methyl ester (608-16-2) → biotin hydrazide (66640-86-6,1214641-84-5)

Guidance literature:

With hydrazine; In methanol; at 20 ℃;

DOI:10.1080/14756366.2021.2013832

Reference yield: 100.0%

biotin chloride (91853-90-6) → biotin hydrazide (66640-86-6,1214641-84-5)

Guidance literature:

With hydrazine;

DOI:10.1021/bc9005656

Reference yield:

biotin (58-85-5,22879-79-4) → biotin hydrazide (66640-86-6,1214641-84-5)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride / methanol

2: hydrazine hydrate / Heating

With thionyl chloride; hydrazine hydrate; In methanol;

DOI:10.1016/j.bmcl.2014.08.030

upstream raw materials:

biotin methyl ester

biotin chloride

biotin