2-((4-Chlorobenzyl)oxy)-5-nitrobenzaldehyde

Base Information

Chemical Name:2-((4-Chlorobenzyl)oxy)-5-nitrobenzaldehyde
CAS No.:114483-64-6
Molecular Formula:C₁₄H₁₀ClNO₄
Molecular Weight:291.691
Hs Code.:
DSSTox Substance ID:DTXSID801242192
Mol file:114483-64-6.mol

Synonyms:2-((4-Chlorobenzyl)oxy)-5-nitrobenzaldehyde;114483-64-6;2-[(4-chlorophenyl)methoxy]-5-nitrobenzaldehyde;DTXSID801242192;AKOS000287467

Suppliers and Price of 2-((4-Chlorobenzyl)oxy)-5-nitrobenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-((4-Chlorobenzyl)oxy)-5-nitrobenzaldehyde

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:291.0298355
Heavy Atom Count:20
Complexity:339

Purity/Quality:: ≥99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1COC2=C(C=C(C=C2)[N+](=O)[O-])C=O)Cl

Technology Process of 2-((4-Chlorobenzyl)oxy)-5-nitrobenzaldehyde

There total 1 articles about 2-((4-Chlorobenzyl)oxy)-5-nitrobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 104-83-6
1-Chloro-4-(chloromethyl)benzene

: 97-51-8
5-Nitrosalicylaldehyde

: 114483-64-6
2-((4-chlorobenzyl)oxy)-5-nitrobenzaldehyde

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.bmc.2016.04.022

Reference yield: 90.3%

: 123-30-8
4-amino-phenol

: 114483-64-6
2-((4-chlorobenzyl)oxy)-5-nitrobenzaldehyde

: 4-((2-((4-chlorobenzyl)oxy)-5-nitrobenzyl)amino)phenol

Guidance literature:: 4-amino-phenol; 2-((4-chlorobenzyl)oxy)-5-nitrobenzaldehyde; With acetic acid; In methanol; at 20 ℃; Inert atmosphere;

With sodium cyanoborohydride; In methanol; Inert atmosphere;
DOI:10.1016/j.bmc.2016.04.022

Reference yield:

: 114483-64-6
2-((4-chlorobenzyl)oxy)-5-nitrobenzaldehyde

: 103293-65-8
ethyl 4-[2-(4-chlorobenzyloxy)-5-nitrophenyl]-2-phenyl-6-methyl-5-pyrimidinecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: piperidine, AcOH / benzene / 1 h / Heating

2: 85.9 percent / Et₃N / butan-1-ol / 1.5 h / Heating

3: 60.6 percent / MnO₂ / CHCl₃ / 2 h / Heating

With piperidine; manganese(IV) oxide; acetic acid; triethylamine; In chloroform; butan-1-ol; benzene;
DOI:10.1248/cpb.40.1452