(3S,6aS,9S,10R,10aR)-4-formyl-3,10-dihydroxy-7,7-dimethyl-1-oxo-3,3a,6,6a,7,8,9,10-octahydronaphtho[1,8a-c]furan-9-yl 2-hydroxyoctanoate

Base Information

• Chemical Name: (3S,6aS,9S,10R,10aR)-4-formyl-3,10-dihydroxy-7,7-dimethyl-1-oxo-3,3a,6,6a,7,8,9,10-octahydronaphtho[1,8a-c]furan-9-yl 2-hydroxyoctanoate
• CAS No.: 158761-00-3
• Molecular Formula: C₂₃H₃₄O₈
• Molecular Weight: 438.518
• Mol file: 158761-00-3.mol

Synonyms:1H-Naphtho[1,8a-c]furan,octanoic acid deriv.; Mniopetal C

Chemical Property of (3S,6aS,9S,10R,10aR)-4-formyl-3,10-dihydroxy-7,7-dimethyl-1-oxo-3,3a,6,6a,7,8,9,10-octahydronaphtho[1,8a-c]furan-9-yl 2-hydroxyoctanoate

Chemical Property:

• Vapor Pressure: 4.08E-19mmHg at 25°C
• Boiling Point: 640.7°Cat760mmHg
• Flash Point: 216.6°C
• Density: 1.28g/cm³

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3S,6aS,9S,10R,10aR)-4-formyl-3,10-dihydroxy-7,7-dimethyl-1-oxo-3,3a,6,6a,7,8,9,10-octahydronaphtho[1,8a-c]furan-9-yl 2-hydroxyoctanoate

There total 11 articles about (3S,6aS,9S,10R,10aR)-4-formyl-3,10-dihydroxy-7,7-dimethyl-1-oxo-3,3a,6,6a,7,8,9,10-octahydronaphtho[1,8a-c]furan-9-yl 2-hydroxyoctanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

C32H50O11 (1450835-85-4) → mniopetal C (158761-00-3)

Guidance literature:

With zinc dibromide; In dichloromethane;

DOI:10.1055/s-0033-1339172

Reference yield:

C20H26O5 (1450835-81-0) → mniopetal C (158761-00-3)

Guidance literature:

Multi-step reaction with 3 steps

1: osmium(VIII) oxide / tetrahydrofuran; water

2: dmap; dicyclohexyl-carbodiimide / dichloromethane / 0 - 20 °C

3: zinc dibromide / dichloromethane

With dmap; osmium(VIII) oxide; dicyclohexyl-carbodiimide; zinc dibromide; In tetrahydrofuran; dichloromethane; water; 2: |Steglich Esterification;

DOI:10.1055/s-0033-1339172

Reference yield:

oct-1-ene (111-66-0,25068-25-1) → mniopetal C (158761-00-3)

Guidance literature:

Multi-step reaction with 8 steps

1: AD-mix β / tert-butyl alcohol; water

2: N,N-dimethyl-formamide

3: dichloromethane

4: tetrabutyl ammonium fluoride / tetrahydrofuran

5: Dess-Martin periodane / dichloromethane

6: sodium chlorite / tert-butyl alcohol

7: dmap; dicyclohexyl-carbodiimide / dichloromethane / 0 - 20 °C

8: zinc dibromide / dichloromethane

With dmap; sodium chlorite; AD-mix β; tetrabutyl ammonium fluoride; Dess-Martin periodane; dicyclohexyl-carbodiimide; zinc dibromide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol; 1: |Sharpless Asymmetric Epoxidation / 7: |Steglich Esterification;

DOI:10.1055/s-0033-1339172

upstream raw materials:

C₂₀H₂₈O₇

C₁₂H₂₄O₅

C₂₀H₂₆O₅

oct-1-ene