1-((4-Chlorophenyl)diphenylmethyl)-1H-imidazole

Base Information

Chemical Name:1-((4-Chlorophenyl)diphenylmethyl)-1H-imidazole
CAS No.:23593-71-7
Molecular Formula:C22H17ClN2
Molecular Weight:344.843
Hs Code.:
European Community (EC) Number:641-535-5
UNII:ZWC2DU38NE
DSSTox Substance ID:DTXSID50517375
Nikkaji Number:J363.067F
Wikidata:Q82379346
Mol file:23593-71-7.mol

Synonyms:23593-71-7;Clotrimazole Impurity A;para-Clotrimazole Isomer;1-((4-Chlorophenyl)diphenylmethyl)-1H-imidazole;1-[(4-Chlorophenyl)diphenylmethyl]-1H-imidazole;1-[(4-chlorophenyl)-diphenylmethyl]imidazole;ZWC2DU38NE;CDD-3532;1-((p-Chlorophenyl)diphenylmethyl)imidazole;1H-Imidazole, 1-((4-chlorophenyl)diphenylmethyl)-;Clotrimazole Imp. B (EP);Clotrimazole Impurity B;CDD 3532;UNII-ZWC2DU38NE;Clotrimazole impurity B [EP];SCHEMBL7156136;DTXSID50517375;BLNLHAFFGFCSRK-UHFFFAOYSA-N;BS-45161;CLOTRIMAZOLE IMPURITY B [EP IMPURITY];FT-0665134;F77628;1-(p-Chloro-alpha,alpha-diphenylbenzyl)imidazole;1-[(4-Chlorophenyl)(diphenyl)methyl]-1H-imidazole;1-[(p-chlorophenyl)-(bisphenyl)-methyl]-imidazole

Suppliers and Price of 1-((4-Chlorophenyl)diphenylmethyl)-1H-imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
para-ClotrimazoleIsomer
500mg
$ 1455.00

Total 15 raw suppliers

Chemical Property of 1-((4-Chlorophenyl)diphenylmethyl)-1H-imidazole

Chemical Property:

Boiling Point:475.9±40.0 °C(Predicted)
PKA:6.28±0.30(Predicted)
PSA：17.82000
Density:1.13±0.1 g/cm3(Predicted)
LogP:5.37670
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:344.1080262
Heavy Atom Count:25
Complexity:388

Purity/Quality:

99.0% Min ^*data from raw suppliers

para-ClotrimazoleIsomer ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)Cl)N4C=CN=C4
Uses para-Clotrimazole Isomer is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rode nts. para-Clotrimazole Isomer (Clotrimazole EP Impurity B) is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rodents.

Technology Process of 1-((4-Chlorophenyl)diphenylmethyl)-1H-imidazole

There total 3 articles about 1-((4-Chlorophenyl)diphenylmethyl)-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6922-89-0
p-chlorotriphenylmethanol

: 23593-71-7
CDD3532

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / Heating

2: triethylamine / acetonitrile / Heating

With thionyl chloride; triethylamine; In acetonitrile;