8-Benzyl-2-methyl-4-phenyl-2,8-diazaspiro[4.5]decane

Base Information

Chemical Name:8-Benzyl-2-methyl-4-phenyl-2,8-diazaspiro[4.5]decane
CAS No.:79139-62-1
Molecular Formula:C22H28N2
Molecular Weight:320.47112
Hs Code.:
DSSTox Substance ID:DTXSID301185834

Synonyms:79139-62-1;8-Benzyl-2-methyl-4-phenyl-2,8-diazaspiro[4.5]decane;SCHEMBL5559764;VQNNVGOTFJJLBG-UHFFFAOYSA-N;DTXSID301185834;ASN 09583879;SR-01000374443;SR-01000374443-1;(rac)-8-benzyl-2-methyl-4-phenyl-2,8-diaza-spiro[4.5]decane;2-Methyl-4-phenyl-8-(phenylmethyl)-2,8-diazaspiro[4.5]decane

Suppliers and Price of 8-Benzyl-2-methyl-4-phenyl-2,8-diazaspiro[4.5]decane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 8-Benzyl-2-methyl-4-phenyl-2,8-diazaspiro[4.5]decane

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:320.225248902
Heavy Atom Count:24
Complexity:387

Purity/Quality:: ≥99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CC(C2(C1)CCN(CC2)CC3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 8-Benzyl-2-methyl-4-phenyl-2,8-diazaspiro[4.5]decane

There total 7 articles about 8-Benzyl-2-methyl-4-phenyl-2,8-diazaspiro[4.5]decane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 6698-80-2
3-methyl-1-phenyl-8-benzyl-3,8-diazaspiro<4,5>decane-2,4-dione

: 79139-62-1
3-methyl-1-phenyl-8-benzyl-3,8-diazaspiro<4,5>decane

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 6h; Heating;

Reference yield: 60.0%

: 79139-62-1
3-methyl-1-phenyl-8-benzyl-3,8-diazaspiro<4,5>decane

Guidance literature:

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 79139-62-1
3-methyl-1-phenyl-8-benzyl-3,8-diazaspiro<4,5>decane

Guidance literature:: Multi-step reaction with 4 steps

1: sodium ethoxide / ethanol / 3 h / Heating

2: 2.) hydrochloric acid / 1.) water, ethanol, reflux, 60 h; 2.) water, reflux, 30 h

3: 1.) sodium ethoxide / 1.) ethanol, 20 min; 2.) ethanol, dimethylformamide, 90 deg C, 3 h

4: 80 percent / lithium aluminiumhydride / tetrahydrofuran / 6 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; sodium ethanolate; In tetrahydrofuran; ethanol;