1-((9H-Fluoren-9-yl)Methyl) 2-tert-butyl pyrazolidine-1,2-dicarboxylate

Base Information

• Chemical Name: 1-((9H-Fluoren-9-yl)Methyl) 2-tert-butyl pyrazolidine-1,2-dicarboxylate
• CAS No.: 222854-34-4
• Molecular Formula: C23H26N2O4
• Molecular Weight: 394.46
• Mol file: 222854-34-4.mol

Synonyms:1-(9H-fluoren-9-yl)methyl 2-tert-butyl pyrazolidine-1,2-dicarboxylate;1-Boc-2-FMOC-pyrazolidine;1-tert-butyl 2-(9H-fluoren-9-ylmethyl) pyrazolidine-1,2-dicarboxylate;1-((9H-Fluoren-9-yl)methyl) 2-tert-butyl pyrazolidine-1,2-dicarboxylate;N-(tert-butoxycarbonyl)-N'-(9-fluorenylmethoxycarbonyl)pyrazolidine;

Chemical Property of 1-((9H-Fluoren-9-yl)Methyl) 2-tert-butyl pyrazolidine-1,2-dicarboxylate

Chemical Property:

• Melting Point: 28-32 °C
• Boiling Point: 506.7±43.0 °C(Predicted)
• PKA: -1.93±0.20(Predicted)
• PSA: 59.08000
• Density: 1.232±0.06 g/cm3(Predicted)
• LogP: 4.66910
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1-((9H-Fluoren-9-yl)methyl)2-tert-butylpyrazolidine-1,2-dicarboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-((9H-Fluoren-9-yl)Methyl) 2-tert-butyl pyrazolidine-1,2-dicarboxylate

There total 2 articles about 1-((9H-Fluoren-9-yl)Methyl) 2-tert-butyl pyrazolidine-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide (82911-69-1) + tert-butyl pyrazolidine-1-carboxylate (57699-91-9) → 1-tert-butyl 2-(9H-fluoren-9-ylmethyl) pyrazolidine-1,2-dicarboxylate (222854-34-4)

Guidance literature:

In dichloromethane;

DOI:10.1021/jm300557t

Reference yield:

→ 1-tert-butyl 2-(9H-fluoren-9-ylmethyl) pyrazolidine-1,2-dicarboxylate (222854-34-4)

Guidance literature:

Reference yield:

1-tert-butyl 2-(9H-fluoren-9-ylmethyl) pyrazolidine-1,2-dicarboxylate (222854-34-4) → fluoren-9-yl-methyl pyrazolidine-1-carboxylate hydrochloride (1093755-81-7)

Guidance literature:

1-tert-butyl 2-(9H-fluoren-9-ylmethyl) pyrazolidine-1,2-dicarboxylate; With trifluoroacetic acid; In dichloromethane; for 1h;

With hydrogenchloride; In water; for 1h;

DOI:10.1021/jm300557t

upstream raw materials:

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

tert-butyl pyrazolidine-1-carboxylate

Downstream raw materials:

fluoren-9-yl-methyl pyrazolidine-1-carboxylate hydrochloride