2-Bromo-2'-Chlorobiphenyl

Base Information

• Chemical Name: 2-Bromo-2'-Chlorobiphenyl
• CAS No.: 107208-70-8
• Molecular Formula: C12H8BrCl
• Molecular Weight: 267.553
• Mol file: 107208-70-8.mol

Synonyms:2-Bromo-2'-Chlorobiphenyl

Chemical Property of 2-Bromo-2'-Chlorobiphenyl

Chemical Property:

• PSA: 0.00000
• LogP: 4.76950
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

2-BROMO-2'-CHLOROBIPHENYL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Bromo-2'-Chlorobiphenyl

There total 7 articles about 2-Bromo-2'-Chlorobiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-Bromo-2-iodobenzene (583-55-1) + 2-Chlorobenzeneboronic acid (3900-89-8) → 2-bromo-2’-chloro-1,1’-biphenyl (107208-70-8)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; In 1,2-dimethoxyethane; water; at 80 ℃; for 5h; Inert atmosphere;

DOI:10.1002/ejoc.201001393

Reference yield: 71.0%

2-bromo-1-chlorobenzene (694-80-4) → 2-bromo-2’-chloro-1,1’-biphenyl (107208-70-8)

Guidance literature:

With n-butyllithium; at -78 - -75 ℃; for 2.5h;

DOI:10.1016/0022-328X(86)80170-X

Reference yield: 68.0%

→ 2-bromo-2’-chloro-1,1’-biphenyl (107208-70-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutylammomium bromide; potassium carbonate; In ethanol; water; toluene; at 60 - 65 ℃; for 12h; Inert atmosphere;

upstream raw materials:

2'-chloro-[1,1'-biphenyl]-2-amine

2-bromo-1-chlorobenzene

1-Bromo-2-iodobenzene

2-Chlorobenzeneboronic acid

Downstream raw materials:

9,9-dimethyl-9-silafluorene

Refernces

• 1、 Corey, Joyce Y.,Chang, Lihsueh S.. "NEW PRECURSORS TO SILAFLUORENES". . p. 7 - 14. Retrieved 1986.
• 2、 -. "COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE". Paragraph 0141-0143. . Retrieved 2022/01/08.
• 3、 -. "Nitrogen-containing compound, organic electroluminescent device, and electronic device". Paragraph 0181-0185. . Retrieved 2020/08/06.