(1'R)- [1,3':1',1'':3'',1'''-Quaternaphthalene]-2',2''-diol

Base Information

• Chemical Name: (1'R)- [1,3':1',1'':3'',1'''-Quaternaphthalene]-2',2''-diol
• CAS No.: 851615-07-1
• Molecular Formula: C₄₀H₂₆O₂
• Molecular Weight: 538.645
• Mol file: 851615-07-1.mol

Synonyms:(1'R)- [1,3':1',1'':3'',1'''-Quaternaphthalene]-2',2''-diol;R-[1,3':1',1'':3'',1'''-Quaternaphthalene]-2',2''-diol

Chemical Property of (1'R)- [1,3':1',1'':3'',1'''-Quaternaphthalene]-2',2''-diol

Chemical Property:

• Boiling Point: 670.0±50.0 °C(Predicted)
• PKA: 8.06±0.50(Predicted)
• PSA: 40.46000
• Density: 1.286±0.06 g/cm3(Predicted)
• LogP: 10.71160

Purity/Quality:

97% ^*data from raw suppliers

(R)-[1,3':1',1'':3'',1'''-Quaternaphthalene]-2',2''-diol, 98% (99% ee) 98% (99% ee) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1'R)- [1,3':1',1'':3'',1'''-Quaternaphthalene]-2',2''-diol

There total 10 articles about (1'R)- [1,3':1',1'':3'',1'''-Quaternaphthalene]-2',2''-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-Naphthylboronic acid (13922-41-3) + (R)-3,3'-diiodo-2,2'-dihydroxy-1,1'-binaphthyl → (R)-(-)-[3,3'-bis(1-naphthyl)-[1,1'-binaphthalene]]-2,2'-diol (851615-07-1,863659-88-5)

Guidance literature:

With palladium on activated charcoal; potassium carbonate; In 1,4-dioxane; water; at 95 ℃; for 8h;

DOI:10.1016/j.tetlet.2014.09.109

Reference yield: 95.0%

C44H34O4 → (S)-[2,2':4',1'':3'',2'''-quaternaphthalene]-2'',3'-diol (851615-07-1,863659-88-5)

Guidance literature:

With hydrogenchloride; methanol; In dichloromethane; water; at 20 ℃; for 6h; Inert atmosphere;

DOI:10.1002/anie.202112671

Reference yield: 87.0%

(Ra)-2,2'-bis(methoxy-methyloxy)-1,1'-binaphthalene + 1-Chloronaphthalene (90-13-1) → (R)-(-)-[3,3'-bis(1-naphthyl)-[1,1'-binaphthalene]]-2,2'-diol (851615-07-1,863659-88-5)

Guidance literature:

(Ra)-2,2'-bis(methoxy-methyloxy)-1,1'-binaphthalene; 1-Chloronaphthalene; With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride; tert.-butyl lithium; In n-heptane; at 20 ℃; for 0.166667h; Schlenk technique;

In n-heptane; Schlenk technique; Acidic conditions;

DOI:10.1002/anie.201707760

upstream raw materials:

1-Naphthylboronic acid

(S)-[1,1']-binaphthalenyl-2,2'-diol

(S)-2,2’-bis(methoxymethoxy)-3,3’-diiodo-1,1’-binaphthalene

1-Bromonaphthalene